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Iranian Journal of Veterinary Medicine، جلد ۱۹، شماره ۳، صفحات ۴۰۵-۴۱۴
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عنوان انگلیسی A Brief Review of Synthesis Methods, Biological Activities, and Cytotoxicity of Cerium Oxide Nanoparticles
چکیده انگلیسی مقاله Cerium oxide nanoparticles (CeO2-NPs, or nanoceria) are among the most unique and promising lanthanide nanomaterials, with unique properties like redox activity, oxygen storage capacity, and free radical scavenging ability. Their ability to self-regenerate their surface makes them potential candidates in different fields, especially the biomedical division. The mechanisms by which nanoceria protect against oxidative stress include direct scavenging of radicals by mimicking the catalytic activity of redox enzymes. Depending on the surface characteristics and environment, nanoceria can act as a double-edged sword and display oxidant and antioxidant properties. Despite their potential for clinical applications, contradictory studies have reported the potential toxicity of CeO2-NPs. This review describes the synthesis methods of CeO2-NPs, the applications of nanoceria for antioxidant, anti-inflammatory, and anticancer activities, including the most recent studies carried out in vivo and in vitro, and their cytotoxic activity. 
کلیدواژه‌های انگلیسی مقاله Cerium oxide nanoparticles (CeO2-NPs),Nanoceria,Antioxidant,synthesis,Cytotoxic activity
نویسندگان مقاله Behnaz Karimi |
Department of Basic Science, Faculty of Veterinary Medicine, Shahrekord University, Shahrekord, Iran

Saman Yousefi |
Department of Pathobiology, Faculty of Veterinary Medicine, Shahrekord Branch, Islamic Azad University, Shahrekord, Iran.

نشانی اینترنتی https://ijvm.ut.ac.ir/article_96902_11379c15f57c339d9378acf92e9e68b0.pdf
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