Background: The present study investigated the tumor stage and its relationship with the microscopic grade and histological pattern of esophageal and stomach cancer in Khorramabad City in Iran to detect it in the early stages.
Materials and Methods: In this cross-sectional study, 109 slides of pathological samples of esophageal and gastric cancer operated at Shohada-ye Ashayer Hospital in Khorramabad from 2006 to 2012 were investigated, and finally, 97 complete samples were obtained. The pattern of the tumor margin was determined by light microscopy, and the tumor grade was determined according to the differentiation of cells and tissues. The marginal histological pattern of the tumor was determined by observing the growth of tumor cells compared to normal tumor cells.
Results: The results of the study indicated that the patients had been referred to the hospital in advanced stages, and no statistically significant relationship was found between tumor stage and grade. There is no statistically significant relationship between tumor stage and infiltration margin; however, a statistically significant relationship was found between tumor stage and budding margin (P<0.05).
Conclusion: The results revealed that most esophageal and stomach cancers in Khorramabad City in Iran are diagnosed in advanced stages, and not even one case was found in the intramucosal and submucosal stages. Considering the prevalence of gastrointestinal cancer in Lorestan province (Iran), there is a need for screening programs and more serious measures to detect esophageal and stomach cancer in the early stages.