این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Nanomedicine Journal، جلد ۱۲، شماره ۳، صفحات ۴۷۳-۴۹۹
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی In-vitro Anti-cancer and Antioxidant Activity of Biogenically Synthesized Co3O4@NiO Core-shell Nanostructures
چکیده انگلیسی مقاله The anticancer and antioxidant activities of Datura stramonium plant leaf extract mediated Co3O4 and NiO nanoparticles, as well as Co3O4@NiO core-shell nanostructures were investigated. The Co3O4@NiO CSNs were synthesized with core-shell concentration ratios of 2:1, 1:1, and 2:3. The Co3O4@NiO CSNs and their parent nanoparticles were characterized by using advanced techniques. The band gap energy of Co3O4 (11) and NiO (11) NPs were found to be 3.06 eV and 3.45 eV, whereas, the band gap energies of the Co3O4 core and NiO shell were 3.68 and 4.52 eV, respectively. Similarly, the average crystalline size of Co3O4 (11) and NiO (11) NPs, as well as Co3O4@NiO (11) CSNs were found to be 18, 12, and 13 nm, respectively. The spherical shape of Co3O4, NiO NPs, and the spherical rod of Co3O4@NiO CSNs were investigated from SEM images. The particle sizes of cubic Co3O4, NiO NPs, and Co3O4@NiO CSNs obtained from TEM images were 15.55, 8.184, and 16.99 nm, respectively. The polycrystalline nature of CN was revealed from SAED analysis The percentage inhibition of Co3O4@NiO CSNs against MCF-7 cancer cells at 100, 200, 400, and 800 μg/mL were found to be 52.41, 68.21, 74.11, and 81.38%, respectively. The IC50 of Co3O4@NiO CSNs and epirubicin were found to be 21.25 and 18.01 μg/mL, respectively. The findings show that green synthesized Co3O4@NiO CSNs possess potential anticancer activities nearly comparable with standard drugs with less toxicity against normal cells.
کلیدواژه‌های انگلیسی مقاله Breast cancer, Anticancer, Antioxidant, Cytotoxicity
نویسندگان مقاله | Gezahegn Ayanie
Applied Chemistry, Applied and Natural Science, Adama Science and Technology University, Adama, Ethiopia


| Tegene Zeleke
Applied Chemistry, Applied and Natural Science, Adama Science and Technology University, Adama, Ethiopia


| H.C Murthy
Department of Applied Sciences, Papua New Guinea University of Technology, Lae, Morobe Province, 411, Papua New Guinea, India


| Lemma Tifa
Applied Chemistry, Applied and Natural Science, Adama Science and Technology University, Adama, Ethiopia


| Addisalem Godana
Research Scholar, School of Chemical Sciences, Indian Institute of Technology Mandi, (IIT Mandi) Himachal Pradesh-175005, India
نشانی اینترنتی https://nmj.mums.ac.ir/article_25747.html
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده مقاله پژوهشی
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات