این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Iranian Journal of Neonatology، جلد ۱۶، شماره ۳، صفحات ۳۱-۴۱
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Predictive Role of the Systemic Immune-Inflammation Index in Catheter-Related Thrombosis among Neonates: A Retrospective Study
چکیده انگلیسی مقاله Background: This study aimed to evaluate changes in hematological parameters and the systemic immune-inflammation index (SII) to determine their utility in predicting and monitoring catheter-related thrombosis (CRT) in neonatal intensive care unit (NICU). We expect that this study will provide novel insights into the potential role of inflammation-based indices in the management of neonatal thrombosis. Methods: A retrospective case-control study was conducted in a tertiary NICU over five years. Infants were divided into three groups: those with CRT, those with central venous catheters but without thrombosis (non-CRT), and healthy controls. Serial complete blood counts (CBCs) were analyzed, including inflammatory indices such as neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), monocyte-to-lymphocyte ratio (MLR), and SII. Results: Compared to the other groups, CRT infants had significantly lower baseline hemoglobin levels and higher levels of white blood cells (WBC), absolute neutrophil count (ANC), NLR, C-reactive protein (CRP), and SII over time (p < 0.05 for all). No significant changes were found in monocyte count, MLR, or mean platelet volume. While SII decreased over time in the control group, it showed a rising trend in CRT infants, indicating ongoing inflammation. Conclusion: Serial measurements of WBC, ANC, NLR, and SII may serve as useful indicators of thrombotic risk in catheterized neonates. These indices may provide better predictive value than standard CBC parameters. Larger multicenter studies are warranted to validate these findings. Larger multicenter studies are needed to confirm these findings.
کلیدواژه‌های انگلیسی مقاله Inflammation, neonatal intensive care, systemic immune-inflammation index (SII), Thrombosis
نویسندگان مقاله | Tugba Barsan Kaya
Division of Neonatology, Department of Pediatrics, Eskisehir Osmangazi University Faculty of Medicine, Eskisehir, Turkiye


| Zeynep Ozdemir
Division of Pediatric Hematology and Oncology, Department of Pediatrics, Eskisehir Osmangazi University Faculty of Medicine, Eskisehir, Turkiye


| Ozge Aydemir
Division of Neonatology, Department of Pediatrics, Eskisehir Osmangazi University Faculty of Medicine, Eskisehir, Turkiye


| Hulya Ozen
Department of Biostatistics, Faculty of Medicine, Gulhane Faculty of Medicine, University of Health Sciences, Ankara, Turkıye


| Simay Armagan
Department of Pediatrics, Eskisehir Osmangazi University Faculty of Medicine, Eskisehir, Turkiye


| Ozge Surmeli Onay
Division of Neonatology, Department of Pediatrics, Eskisehir Osmangazi University Faculty of Medicine, Eskisehir, Turkiye


| Ener Cagrı Dinleyici
Department of Pediatrics, Eskisehir Osmangazi University Faculty of Medicine, Eskisehir, Turkiye


| Ayse Tekin
Division of Neonatology, Department of Pediatrics, Eskisehir Osmangazi University Faculty of Medicine, Eskisehir, Turkiye
نشانی اینترنتی https://ijn.mums.ac.ir/article_26179.html
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده تحقیقی اصیل
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات