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Iranian Journal of Public Health، جلد ۵۴، شماره ۷، صفحات ۱۴۴۴-۱۴۵۱
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عنوان انگلیسی Prevalence and Risk Factors of Carbohydrate Metabolism Disorders among Pregnant Women in Kyrgyzstan
چکیده انگلیسی مقاله Background: We aimed to determine the prevalence of carbohydrate metabolism disorders among pregnant women in Kyrgyzstan based on the 2013 WHO diagnostic criteria, to study their frequency, and to assess the influence of key risk factors on the likelihood of developing gestational diabetes mellitus (GDM) and overt diabetes. Methods: A prospective cohort study was conducted, including 617 pregnant women between 2022 and 2024. All participants underwent an oral glucose tolerance test (OGTT) in the second half of pregnancy. Diagnosis of GDM and overt diabetes was carried out according to WHO criteria. Multivariate logistic regression was used to analyze risk factors. ROC analysis was performed to assess the diagnostic value of the number of risk factors in predicting carbohydrate metabolism disorders. Results: The incidence of GDM was 18.8% (116/617), and overt diabetes — 6.96% (43/617). The main risk factors for GDM were: age over 35 years (P = 0.002), arterial hypertension (P = 0.001), second-degree family history of diabetes (P = 0.001), pre-pregnancy overweight or obesity (P = 0.002), and multiparity (P = 0.000). For overt diabetes, key risk factors included first-degree family history of diabetes (P = 0.034), second-degree family history (P = 0.001), and overweight or obesity (P = 0.018). Conclusion: An increase in the number of risk factors correlates with the incidence of GDM and overt diabetes. However, for GDM, the number of risk factors is not a reliable predictor, highlighting the need for universal screening of all pregnant women. For overt diabetes, the number of risk factors showed satisfactory predictive value.
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نویسندگان مقاله | Roza Sultanalieva
Endocrinology Department, Kyrgyz State Medical Academy, Bishkek, Kyrgyzstan


| Bermet Zhunusova
Therapy Department, International Higher School of Medicine, Bishkek, Kyrgyzstan


| Valeriia Kniazeva
Therapy Department, International Higher School of Medicine, Bishkek, Kyrgyzstan


| Nazgul Abylova
Endocrinology Department, Kyrgyz State Medical Academy, Bishkek, Kyrgyzstan


| Aleksandr Sorokin
Department of Physics, Medical Informatics, and Biology, Kyrgyz Russian Slavic University, Bishkek, Kyrgyzstan
نشانی اینترنتی https://ijph.tums.ac.ir/index.php/ijph/article/view/38208
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