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Iranian Journal of Pathology، جلد ۲۰، شماره ۳، صفحات ۳۳۵-۳۴۳
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عنوان انگلیسی Low Grade Appendiceal Mucinous Neoplasm – A Case Series A Silent Threat with Deadly Consequences
چکیده انگلیسی مقاله Background & Objective: Our study was mainly aimed at identifying the cause, clinical course of the disease, its most dreaded complication pseudomyxoma peritonei and spread to adjacent structures. We have used IHC techniques to know the origin of the tumor where both appendix and ovary were involved.
Case Presentation: We have listed out and discussed in detail 5 cases, each of which have a different clinical course and variation in staging, grading and prognosis. One of the cases had mucin deposits in the ovary, for which IHC was done to confirm the origin of the tumor. Some of the findings were incidental and in others presence of mucin content in the appendix lumen raised clinical suspicion of spread to peritoneum and adjacent structures. Grading and staging is of prime importance as it determines the prognosis and management of the patient respectively.
Conclusion: A ruptured or perforated appendix must warrant for an immediate suspicion of pseudomyxoma peritonei which when untreated can lead to mucinous neoplasms in adjacent organs like ovary and colon. Pseudomyxoma Peritonei (PMP) with simultaneous appendix and ovarian neoplasm should be treated as primary appendiceal tumour. Grading and staging of mucinous neoplasm of appendix and Pseudomyxoma Peritoneii needs a unified approach for standardized diagnostic reporting.
کلیدواژه‌های انگلیسی مقاله Appendiceal Neoplasms,Pseudomyxoma Peritonei,Immunohistochemistry
نویسندگان مقاله S.J. John Joseph Hemnath |
Meenakshi Medical College Hospital and Research Institute, Kanchipuram, Tamilnadu, India

Shanmugapriya M |
Meenakshi Medical College Hospital and Research Institute, Kanchipuram, Tamilnadu, India

Suresh R |
Meenakshi Medical College Hospital and Research Institute, Kanchipuram, Tamilnadu, India

Paleri Madhumita |
Meenakshi Medical College Hospital and Research Institute, Kanchipuram, Tamilnadu, India

Lokeshwari V |
Meenakshi Medical College Hospital and Research Institute, Kanchipuram, Tamilnadu, India

Eswari V |
Meenakshi Medical College Hospital and Research Institute, Kanchipuram, Tamilnadu, India

نشانی اینترنتی https://ijp.iranpath.org/article_726175_17ec16bc53640b84757c60007e835ac1.pdf
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