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Journal of Medical Microbiology and Infectious Diseases، جلد ۱۳، شماره ۳، صفحات ۰-۰
عنوان فارسی
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عنوان انگلیسی Assessment of Hematological Indices as Potential Prognostic Markers in COVID-19 Patients at Taleghani Hospital, Urmia, Iran
چکیده انگلیسی مقاله
Introduction: Rapid and accurate diagnosis of COVID-19 is critical for effective patient management, timely treatment, and mitigating disease transmission. Identifying reliable prognostic markers, such as hematological indices, can enable prompt medical intervention and improve outcomes. This study aimed to investigate the association among mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), and mean corpuscular volume (MCV), measured within the first 10 days of hospital admission, and clinical outcomes (e.g., survival vs. mortality) in COVID-19 patients. Methods: This retrospective study included 173 patients with confirmed COVID-19 (Delta variant) admitted to Taleghani Hospital in Urmia. Complete blood count (CBC) data, including hemoglobin (Hb), mean corpuscular hemoglobin (MCH), mean corpuscular volume (MCV), and white blood cell (WBC) counts, were extracted from electronic medical records. Differences between survivor and non-survivor groups were analyzed using ANOVA with Tukey post hoc test, with statistical significance set at P < 0.05. Results: The median age of all patients was 53 years (IQR: 22–88), with a significant difference between survivors (52 years; IQR: 22–88) and non-survivors (60 years; IQR: 35–85) (P = 0.04). Patients in the non-survivor group had a significantly higher prevalence of comorbidities compared to the survivor group. Patients with diabetes (P=0.327) or hypertension (P=0.797) did not have a significantly higher prevalence in the non-survivor group, though trends suggest possible increased mortality risk. However, no significant differences were found in Hb, MCH, and MCV between the survivor and non-survivor groups (P>0.05). Conclusions: While some hematological markers are routinely used in diagnosing various diseases, this study did not find significant differences in Hb, MCH, and MCV between survivor and non-survivor groups, suggesting these specific markers may not be reliable for early diagnosis or predicting prognosis in Delta-variant COVID-19 in this Iranian cohort. Further research with a larger sample size and including a wider range of hematological and inflammatory markers is warranted to explore the potential role of these markers in COVID-19 diagnosis and prognosis. Investigating the interplay between these markers and clinical outcomes could provide valuable insights for patient management.
 
کلیدواژه‌های انگلیسی مقاله COVID-19, Prognosis, Hematological indices, Early diagnosis, Hospitalized patients, Mean corpuscular volume, Mean corpuscular hemoglobin
نویسندگان مقاله | Sahar Mehranfar
Department of Genetics and Immunology, Urmia University of Medical Sciences, Urmia, Iran


| Ali Yekanlou
Student Research Committee, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran


| Mohammad Heidari
Department of Epidemiology and Biostatistics, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran


| Masoud Lahouty
Department of Microbiology and Virology, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran
نشانی اینترنتی http://jommid.pasteur.ac.ir/browse.php?a_code=A-10-576-1&slc_lang=en&sid=1
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زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Other
نوع مقاله منتشر شده Original article
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