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Journal of Medical Bacteriology، جلد ۱۳، شماره ۳، صفحات ۱۱۵-۱۱۷
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عنوان انگلیسی Aptamer Biosensors: Rapid Heterogeneous Vancomycin-Intermediate Staphylococcus aureus Detection Solution
چکیده انگلیسی مقاله Vancomycin is an essential glycopeptide antibiotic facing challenges from resistant bacterial strains such as vancomycin-intermediate Staphylococcus aureus (VISA) and heterogeneous VISA (hVISA). Timely and precise identification of these strains is vital for efficient infection control. This report explores using aptamer-based biosensors as a novel solution for the rapid detection of hVISA. Aptamers, short, single-stranded nucleic acids, exhibit remarkable specificity and strong affinity for their targets, making them outstanding candidates for biosensor creation. These biosensors offer affordability, ease of customization, and swift performance, making them highly appropriate for medical settings. By utilizing electrochemical detection techniques, aptamer-based biosensors facilitate real-time tracking of vancomycin concentrations and may also contribute to the efficient detection of hVISA, addressing urgent demands in infectious disease control.
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نویسندگان مقاله | Hamid Sadeghi
1 Medical Microbiology Research Center, Qazvin University of Medical Sciences, Qazvin, Iran. 2 Student Research Committee, Qazvin University of Medical Sciences, Qazvin, Iran.


| Farhad Nikkhahi
Medical Microbiology Research Center, Qazvin University of Medical Sciences, Qazvin, Iran.


| Susan Khanjani
Medical Microbiology Research Center, Qazvin University of Medical Sciences, Qazvin, Iran.


| Saeideh Gholamzadeh Khoei
Cellular and Molecular Research Center, Research Institute for Prevention of Non-Communicable Diseases, Qazvin University of Medical Sciences, Qazvin, Iran.


| Mohammad Maleki
Clinical Research Development Unit, Kowsar Hospital, Qazvin University of Medical Sciences, Qazvin, Iran.


| Masoumeh Aslanimehr
Medical Microbiology Research Center, Qazvin University of Medical Sciences, Qazvin, Iran.
نشانی اینترنتی https://jmb.tums.ac.ir/index.php/jmb/article/view/569
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