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Journal of Craniomaxillofacial Research، جلد ۱۲، شماره ۱، صفحات ۱۷-۲۵
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عنوان انگلیسی Clinicopathologic Study on Odontogenic Tumors-A 10-Year Single Institute Experience
چکیده انگلیسی مقاله Introduction: Odontogenic tumors are the expansile group of jaw neoplasm that originates from the tooth-forming tissues. WHO, revised classification several times due to their discrete histological and biological behavior. They were broadly classified as benign and malignant tumors, the former being the most common. Benign tumors are classified into epithelial, mixed (epithelial and mesenchymal), and mesenchymal lesions based on their histogenetic origin.  Materials and Methods: 1. To evaluate the various types of odontogenic tumors diagnosed in the Department of Oral Pathology. 2. To correlate the clinical data and histological features of odontogenic tumors diagnosed. Clinical data of all the odontogenic tumors were collected retrospectively from the 10-year archives of the Oral Pathology Department, GITAM Dental College and Hospital, Visakhapatnam. The tumors were classified according to the WHO classification. Clinical and histopathological evaluations wasere doneperformed for all the odontogenic tumors. Different histological characteristics were compared; tabulated and analyzed. Results: A total of 105 cases of odontogenic tumors were recorded. 82% account for benign tumors, and 18% for malignant tumors. Epithelial origins comprise the majority of benign tumors (48%), followed by mesenchymal and mixed odontogenic tumors (20% and 14%, respectively). Unicystic ameloblastoma is the most common odontogenic tumor, accounting for 18 (17%) cases, followed by conventional ameloblastoma, odontogenic fibroma, ameloblastic carcinoma, and odontoma. Odontogenic tumors were reported mostly during the second, third, and fourth decades of life. Male predilection was observed over females in all the odontogenic tumors. All forms of OT were detected in the posterior mandible. Epithelial odontogenic tumors predominate in all four anatomical sites, except the posterior maxilla, where mesenchymal OT was somewhat more common and no malignant odontogenic tumor was seen.  Conclusion: The variability in data from this study can be ascribed to a variety of demographic factors. Hence, the need to incorporate specific lesion histopathology and diagnostic molecular interventions would make results more sensitive catering to research needs.  Keywords: WHO Classification; Odontogenic; Tumors; Ameloblastoma; Odontoma.
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نویسندگان مقاله | UDN Sreevalli
Department of Oral Pathology and Microbiology, GITAM Dental College and Hospital, Visakhapatnam, Andhra Pradesh, India.


| Divya Uppala
Department of Oral Pathology and Microbiology, GITAM Dental College and Hospital, Visakhapatnam, Andhra Pradesh, India.


| Buddha Harika Varshita
Department of Oral Pathology and Microbiology, GITAM Dental College and Hospital, Visakhapatnam, Andhra Pradesh, India.
نشانی اینترنتی https://jcr.tums.ac.ir/index.php/jcr/article/view/544
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