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Iranian Journal of Pathology، جلد ۲۰، شماره ۴، صفحات ۳۶۷-۳۷۹
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عنوان انگلیسی Trichosporon Urinary Tract Infections: A Hidden Menace Revealed
چکیده انگلیسی مقاله Urinary tract infections (UTIs) caused by Trichosporon are a significant concern for hospitalized patients and those with weakened immune systems. This narrative review study aims to provide a comprehensive overview of UTIs caused by Trichosporon, including its frequency, risk factors, laboratory diagnostic aspects, drug resistance, and the importance of accurate identification in clinical settings. A search of international databases was conducted to identify relevant studies, and it was found that Trichosporon asahii, specifically the G1 type, is the predominant causative agent of UTIs among various Trichosporon species. Prolonged hospitalization and immunosuppressive drug use were identified as significant risk factors for this fungal infection. Conventional methods for laboratory identification are commonly used. Still, rapid and accurate tools such as Matrix-Assisted Laser Desorption-Ionisation-Time of Flight Mass Spectrometry (MALDI-TOF MS) and DNA sequencing can improve the diagnostic process. Against all T. asahii isolates for which this triazole, polyene, and echinocandin were tested, voriconazole demonstrated the most potent in vitro activity, while amphotericin B had high MIC values and echinocandins had inherent resistance. This review provides valuable insights into the clinical significance and management of UTIs caused by Trichosporon.
کلیدواژه‌های انگلیسی مقاله Microbial Sensitivity Test,Cutaneotrichosporon,Trichosporon,Urinary tract infections
نویسندگان مقاله Ahmad Elmimoghaddam |
Medical Biotechnology Research Center, AJA University of Medical Sciences, Tehran, Iran

Mahmoud Vahidi |
Medical Biotechnology Research Center, AJA University of Medical Sciences, Tehran, Iran

Reza Heidari |
Medical Biotechnology Research Center, AJA University of Medical Sciences, Tehran, Iran

Mahdi Ghorbani |
Department of Medical Laboratory Sciences, School of Allied Medical Sciences, AJA University of Medical Sciences, Tehran, Iran

Peyman Aslani |
Department of Parasitology & Mycology, Faculty of Medicine, AJA University of Medical Sciences, Tehran, Iran

نشانی اینترنتی https://ijp.iranpath.org/article_728536_1f7a3da7384448a37d824c79bfc2c736.pdf
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