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Iranian Journal of Veterinary Science and Technology، جلد ۱۷، شماره ۳، صفحات ۳۸-۴۶

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عنوان انگلیسی Preliminary Evaluation of the Therapeutic Effects of Neem Leaf Extract and Ivermectin in West African Dwarf Goats with Clinical Mange
چکیده انگلیسی مقاله This study investigates the therapeutic potential of neem (Azadirachta indica) extract as a topical remedy for mange in West African Dwarf (WAD) goats, a breed commonly raised in Southern Nigeria and are affected by mange, which negatively impacts animal welfare and productivity. Twelve mange-infected goats were randomly assigned to three treatment groups: T1 (10 ml ivermectin pour-on), T2 (5 ml neem extract + 5 ml ivermectin), and T3 (10 ml neem extract). Treatments were administered topically over 14 day period.  Clinical evaluations included skin scrapings, red blood cell (RBC), white blood cell (WBC) and serum biochemical indices.  Phytochemical analysis of the neem extract revealed notable concentrations of alkaloids, saponins, and phenols.  Post-treatment observations showed improvement in skin condition across all groups. Notably, T2 goats exhibited significant increases in RBC and WBC counts (p < 0.05). Differences in serum biochemical indices, particularly potassium, were also noted. The findings indicate that neem extract, can serve as an effective alternative or adjunct treatment to ivermectin for mange control in WAD goats. Its use may be particularly beneficial in local environments with poor accesibility to conventional drugs, contributing to improve animal health and production outcomes.
کلیدواژه‌های انگلیسی مقاله Neem leaf,Ivermectin,Mange,West African Dwarf goats,Topical,Food security

نویسندگان مقاله Olubunmi Titilayo Ojoawo |
Department of Animal Production and Health, Faculty of Agricultural Sciences, Ladoke Akintola University of Technology, Nigeria.

Jelili Akinwole Akinlade |
Department of Animal Production and Health, Faculty of Agricultural Sciences, Ladoke Akintola University of Technology, Nigeria.

Opeyemi Agbeniyi |
Department of Animal Production and Health, Faculty of Agricultural Sciences, Ladoke Akintola University of Technology, Nigeria.

Opeyemi Oladipupo Hammed |
Department of Animal Production and Health, Faculty of Agricultural Sciences, Ladoke Akintola University of Technology, Nigeria.

Fiwasade Adejoke Rom-Kalilu |
Department of Animal Production and Health, Faculty of Agricultural Sciences, Ladoke Akintola University of Technology, Nigeria.


نشانی اینترنتی https://ijvst.um.ac.ir/article_46923_4c8e2b0d1a73941270023c272e1865f8.pdf
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