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عنوان انگلیسی Comparison of Efficacy of Nebulized Ventolin, Pulmicort and Normal Saline in Treatment of Children Under 2 Years Old with Bronchiolitis Admitted in Ahvaz Abuzar Hospital
چکیده انگلیسی مقاله Background: Bronchiolitis is a common lower respiratory tract infection in infants. Apart from supportive care, no effective treatment for this disease has been identified so far. Accordingly, a double-blind randomized controlled trial was conducted on infants with a diagnosis of mild to moderate bronchiolitis. Material and Methods: Three clinical trial groups were designed, including Ventolin 0.15 mg/kg, Palmicort 125 mg twice a day, and normal saline nebulization every 4 hours. Clinical symptoms were monitored by asthma and allergy specialist daily, and the need for supplemental oxygen, recovery time from symptoms, and hospital days were recorded and compared between the three groups. Results: The results demonstrated that the frequency of oxygen requirement in both palmicort and normal saline groups was lower in compare to the ventolin group. But there was no significant difference between the three groups (P=0.765 and P=0.907, respectively). The duration of symptom improvement in the normal saline and palmicort group was significantly shorter than the Ventolin group (P=0.017). No significant difference was observed between the three groups of Ventolin, Pulmicort and normal saline during the treatment in terms of clinical score (P≥0.05). Conclusion: The obtained results showed that Ventolin or Palmicort nebulizer is not statistically better than normal saline for the treatment of children with bronchiolitis. Therefore, our results do not support the routine use of bronchodilators in the clinical setting for the management of mild to moderate forms of bronchiolitis in infants.
کلیدواژه‌های انگلیسی مقاله Bronchiolitis,Ventolin,Pulmicort,Nebulizer,Normal Saline,Infants
نویسندگان مقاله Mahsa Abdollah Zadeh |
Department of Pediatrics Pulmonology, Abuzar Children's Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

Farhad Abolnejadian |
Department of Pediatrics Pulmonology, Abuzar Children's Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

Mohsen Alisamir |
Infectious and Tropical Diseases Research Center, Health Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

Mohammad Reza Mirkarimi |
Department of Pediatric Pulmonology, Abuzar Children’s Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

Mehdi Torabizadeh |
Golestan Hospital Clinical Research Development Unit, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

نشانی اینترنتی https://mjms.modares.ac.ir/article_19514_4a0128e6aa773e3afcd6040a3a96b391.pdf
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