این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Bulletin of Emergency and Trauma، جلد ۱۳، شماره ۳، صفحات ۰-۰
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Effects of Intravenous Lidocaine on Airway Complications and Hemodynamic Stability Following Emergency Laparoscopic Cholecystectomy: A Randomized Controlled Trial in Different Age Groups
چکیده انگلیسی مقاله Objectives: This randomized controlled trial aimed to evaluate the effect of pre-extubation intravenous
lidocaine (1 mg/Kg) on the incidence of airway complications and hemodynamic stability in patients undergoing
emergency laparoscopic cholecystectomy, while accounting for age differences.
Methods: The study was a prospective, single-center, randomized controlled trial conducted from 2021 to 2023
at Imam Khomeini Hospital, Ilam, Iran. Ninety patients undergoing emergency laparoscopic cholecystectomy
were classified into two age groups (<50 and ≥50 years) and randomly assigned to receive either intravenous
lidocaine (1 mg/Kg) or a standard extubation protocol. The primary outcomes included post-extubation
airway complications, such as laryngospasm, cough, and sore throat, and the secondary outcomes included
hemodynamic and respiratory parameters.
Results: Lidocaine produced hemodynamic effects that differed by age group. In patients <50 years, systolic
blood pressure (SBP) increased from 129.2±16.4 mmHg to 133.1±23.1 mmHg, while diastolic blood pressure
(DBP) rose from 83.9±14.4 mmHg to 92.3±19.4 mmHg (both p<0.001). Conversely, in patients ≥50 years old,
SBP decreased from 160.5±26.7 mmHg to 145.2±19.7 mmHg, and DBP decreased from 107.9±19.5 mmHg to
99.0±16.1 mmHg (both p<0.001). Airway complications exhibited non-significant tendencies, with a decreased
incidence of cough in the older age group (15.6% vs. 31.8%) and an absence of laryngospasm in this age group.
There were no serious adverse events (e.g., bronchospasm, arrhythmias).
Conclusion: Intravenous lidocaine was safe and demonstrated a trend toward reducing airway complications
at extubation in patients undergoing emergency laparoscopic cholecystectomy, particularly in elderly patients.
However, this trend did not reach statistical significance, most likely due to insufficient statistical power.
کلیدواژه‌های انگلیسی مقاله Lidocaine,Cholecystectomy,Laparoscopic,Hemodynamic
نویسندگان مقاله Mohammad Mohammadifard |
Anesthesia Department, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran

Kowsar Ali Akbari |
Anesthesia Department, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran

Pooyan Ahanrobai |
Anesthesiology Department, Imam Khomeini Hospital, Ilam University of Medical Sciences, Ilam, Iran

Aminolah Vasigh |
Anesthesia Department, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran

نشانی اینترنتی https://beat.sums.ac.ir/article_51151_124f3e2b7e82b053e73c66ee74406f0c.pdf
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات