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Journal of Agricultural Science and Technology، جلد ۲۶، شماره ۴، صفحات ۸۷۳-۸۸۴
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عنوان انگلیسی Herbicidal and Insecticidal Activity of Secondary Metabolites from Endophytic and Soil Fungi
چکیده انگلیسی مقاله Fungi are a good source for lead molecules in drug discovery and development. However, many compounds derived from fungi were not evaluated for their bioactivity against economic, agricultural, and public health pests. Twelve fungal secondary metabolites (1-12) were evaluated for herbicidal activity against Silybum marianum and insecticidal activity against Culex pipiens larvae. Among the tested metabolites, brefeldin A (6) and 6-eopxy-4-hydroxy-3-methoxy-5-methyl-cyclohex-2-en-1-one (11) showed potent herbicidal activity against S. marianum with complete inhibition of seed germination at 500 mg L−1. Compound 6 revealed an exceptional herbicidal activity as it caused complete inhibition of root growth and strong reduction in shoot growth (I = 74.5%) and germination (10.0%) at 25 mg L−1. In addition, dehydroaustin (9), phomaxanthone A (4) and deacetylphomaxanthone A (5) displayed a potent toxicity against fourth larval instar of C. pipiens with LC50 values of 3.27, 57.03 and 63.50 mg L−1, respectively. Based on the results of this study, compounds 4-6, 9 and 11 should be developed as natural pesticides.
کلیدواژه‌های انگلیسی مقاله Bioactivity,Culex pipiens,Fungal metabolites,Natural products,Silybum marianum
نویسندگان مقاله S. Abdelgaleil |
Department of Pesticide Chemistry and Technology, Faculty of Agriculture, El-Shatby, Alexandria University, Alexandria 21545, Egypt.

Y. Shiono |
Department of Food, Life, and Environmental Science, Faculty of Agriculture, Yamagata University, Tsuruoka, Yamagata, 997-8555, Japan.

N. E. M. Taktak |
Department of Tropical Health, High Institute of Public Health, Alexandria University, Alexandria, Egypt.

M. M. G. Saad |
Department of Pesticide Chemistry and Technology, Faculty of Agriculture, El-Shatby, Alexandria University, Alexandria 21545, Egypt.

نشانی اینترنتی https://jast.modares.ac.ir/article_16960_13f9eacf5a1fc8d6c5ae4c583d7b8e69.pdf
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