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International Journal of Fertility and Sterility، جلد ۱۹، شماره ۴، صفحات ۳۴۴-۳۵۲
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عنوان انگلیسی The Role of Nutrition in Endometriosis Prevention and Management: A Comprehensive Review
چکیده انگلیسی مقاله Endometriosis is a chronic gynecological condition defined by the ectopic presence of endometrial-like tissue outside
the uterine cavity, often resulting in debilitating symptoms and significant impacts on quality of life. While the exact
etiology of endometriosis remains elusive, emerging evidence suggests that diet and nutrition may play a crucial role
in its pathogenesis and management. This comprehensive review explores the complex interplay between various
food substances and endometriosis, summarizing the latest research findings on both risk-enhancing and protective
nutritional factors. Notably, consumption of alcohol, red and processed meats, foods high in saturated and trans fats,
and excessive caffeine has been correlated with increased systemic inflammation and hormonal dysregulation-key
mechanisms implicated in endometriosis pathogenesis. In contrast, nutrients such as antioxidants, B-complex vitamins,
vitamin D, calcium, polyunsaturated fatty acids (PUFAs, particularly omega-3 and omega-6), and dietary fiber
have shown promise in exerting anti-inflammatory and protective effects against endometriosis. The review emphasizes
the importance of promoting a balanced and nutritious diet rich in anti-inflammatory and antioxidant-rich food
while limiting the intake of pro-inflammatory substances for individuals with endometriosis. In addition to dietary
interventions, lifestyle modifications, including regular physical activity, stress management, and optimizing sleep
hygiene, are highlighted as integral components of comprehensive treatment plans for endometriosis patients. Further
research is required to clarify the precise mechanisms underlying the relationship between diet and endometriosis and
to establish evidence-based dietary recommendations personalized for patients with endometriosis.
کلیدواژه‌های انگلیسی مقاله Diet,Endometriosis,inflammatory factors,Nutrition,protective factors
نویسندگان مقاله R Muharam |
Reproductive Immunoendocrinology Division, Department of Obstetrics and Gynecology, Faculty of Medicine Universitas Indonesia -dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia

Edward Christopher Yo |
Reproductive Immunoendocrinology Division, Department of Obstetrics and Gynecology, Faculty of Medicine Universitas Indonesia -dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia

Alisha Nurdya Irzanti |
Reproductive Immunoendocrinology Division, Department of Obstetrics and Gynecology, Faculty of Medicine Universitas Indonesia -dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia

Kresna Mutia |
Human Reproduction, Infertility, and Family Planning Cluster, Indonesia Reproductive Medicine Research and Training Center, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia

Kanadi Sumapraja |
Reproductive Immunoendocrinology Division, Department of Obstetrics and Gynecology, Faculty of Medicine Universitas Indonesia -dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia

Achmad Kemal Harzif |
Reproductive Immunoendocrinology Division, Department of Obstetrics and Gynecology, Faculty of Medicine Universitas Indonesia -dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia

Gita Pratama |
Reproductive Immunoendocrinology Division, Department of Obstetrics and Gynecology, Faculty of Medicine Universitas Indonesia -dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia

Mila Maidarti |
Reproductive Immunoendocrinology Division, Department of Obstetrics and Gynecology, Faculty of Medicine Universitas Indonesia -dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia

Budi Wiweko |
Reproductive Immunoendocrinology Division, Department of Obstetrics and Gynecology, Faculty of Medicine Universitas Indonesia -dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia

Andon Hestiantoro |
Reproductive Immunoendocrinology Division, Department of Obstetrics and Gynecology, Faculty of Medicine Universitas Indonesia -dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia

نشانی اینترنتی https://www.ijfs.ir/article_721837_df509cc2732acebae6f05e833178fd42.pdf
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