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Veterinary Research Forum، جلد ۱۶، شماره ۱۰، صفحات ۵۷۳-۵۷۷
عنوان فارسی
چکیده فارسی مقاله
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عنوان انگلیسی Cathelicidin-1 as a potential biomarker for anestrus detection in cows
چکیده انگلیسی مقاله Cathelicidin-1, an antimicrobial peptide, has garnered attention for its potential role as a biomarker in detecting anestrus in cows, providing insights into bovine reproductive health. This study aimed to analyse cathelicidin-1 within the urinary proteome and evaluate its effectiveness as a diagnostic tool for anestrus in cows. The study employed tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis and matrix-assisted laser desorption ionization-time of flight mass spectrometry techniques to identify and characterize cathelicidin-1 in the context of anestrus in cows. The analysis confirmed the presence and distinct profile of cathelicidin-1, highlighting its significance in reflecting the physiological and pathophysiological states associated with anestrus. Cathelicidin-1 as a promising diagnostic biomarker for anestrus in cows could revolutionize bovine reproductive management by offering more precise and advanced detection methods compared to the traditional, time-consuming, and sometimes inaccurate approaches, like behavioral observation or hormonal assays. If cathelicidin-1 can be detected non-invasively, it would not only enhance early detection and timely intervention but also reduce the need for invasive procedures, thereby improving animal welfare.
کلیدواژه‌های انگلیسی مقاله Anestrus,Antimicrobial peptides,biomarker,Cathelicidin-1,Cow
نویسندگان مقاله Ambika Sharma |
Department of Veterinary Biochemistry, College of Veterinary Science, Uttar Pradesh Pandit Deen Dayal Upadhyaya Pashu Chikitsa Vigyan Vishwavidyalaya Evam Go-Anusandhan Sansthan, Mathura, India

Ashish Kumar |
Department of Pharmacology, All India Institute of Medical Sciences, Rishikesh, India

Arvind Kumar Tripathi |
Department of Veterinary Medicine, College of Veterinary Science, Uttar Pradesh Pandit Deen Dayal Upadhyaya Pashu Chikitsa Vigyan Vishwavidyalaya Evam Go-Anusandhan Sansthan, Mathura, India

Vikas Sachan |
Department of Veterinary Gynaecology and Obstetrics, College of Veterinary Science, Uttar Pradesh Pandit Deen Dayal Upadhyaya Pashu Chikitsa Vigyan Vishwavidyalaya Evam Go-Anusandhan Sansthan, Mathura, India

Pawanjit Singh |
Department of Veterinary Biochemistry, College of Veterinary Science, Uttar Pradesh Pandit Deen Dayal Upadhyaya Pashu Chikitsa Vigyan Vishwavidyalaya Evam Go-Anusandhan Sansthan, Mathura, India

نشانی اینترنتی https://vrf.iranjournals.ir/article_729412_d34861f01c61241c67d8f7202839eb0c.pdf
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