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Veterinary Research Forum، جلد ۱۶، شماره ۱۰، صفحات ۵۸۵-۵۹۰
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عنوان انگلیسی Molecular detection and phylogenetic analysis of feline panleukopenia virus in domestic cat population of Mizoram state, India
چکیده انگلیسی مقاله The most significant infectious disease that affects cats is thought to be feline panleukopenia, also known as Cat distemper. Despite its epidemiological status, few literatures are available regarding the clinic-pathological aspect of the disease and about the molecular epidemiology of the circulating feline panleukopenia virus (FPV) in India. This study gives a comprehensive insight into the prevalence, pathology and diagnosis of FPV in cat population of Mizoram. Twenty-six cats that died of clinical disease suspected of FPV were subjected to a thorough pathological examination followed by molecular diagnosis. The FPV infection was confirmed in 12 out of the 26 cats by polymerase chain reaction assay targeting the VP2 gene of FPV. The phylogenetic analysis based on the full VP2 gene of FPV has demonstrated close genetic affinity of FPV strains circulating in Mizoram with the isolates from Thailand (MW589472), Italy (MZ508524) and China (OR727315). The analysis of the VP2-deduced amino acid sequence revealed two distinct mutations, S179T and I401V, exclusively identified in isolates from this particular study.
کلیدواژه‌های انگلیسی مقاله FPV,Mizoram,Molecular surveillance,pathology,Polymerase chain reaction
نویسندگان مقاله Theresa Zochampuii |
Department of Veterinary Pathology, College of Veterinary Science and Animal Husbandry, Central Agricultural University, Aizawl, India

Tridib Kumar Rajkhowa |
Department of Veterinary Pathology, College of Veterinary Science and Animal Husbandry, Central Agricultural University, Aizawl, India

Kiran Jayappa |
Department of Veterinary Pathology, College of Veterinary Science and Animal Husbandry, Central Agricultural University, Aizawl, India

نشانی اینترنتی https://vrf.iranjournals.ir/article_729409_12386de7ca348efbdd64a201324d5e10.pdf
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