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Iranian Journal of Microbiology، جلد ۱۷، شماره ۵، صفحات ۷۰۲-۷۰۷
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عنوان انگلیسی Serotypes and antibiotic resistance patterns of group B streptococci isolated from pregnant women at Urmia University Hospital, Iran
چکیده انگلیسی مقاله Background and Objectives: Group B Streptococcus (GBS) is a common bacterium found in the gastrointestinal tract and genitalia of both humans and animals. GBS infections can lead to a range of conditions, including meningitis, pneumonia, and sepsis. The present study aimed to analyze the colonization rate, antibiotic susceptibility, and serotypes of GBS in pregnant women in Urmia, Iran. Materials and Methods: Following GBS isolation from pregnant women and confirming its presence through PCR, antibiotic susceptibility testing was conducted to assess resistance patterns, followed by amplification of resistance genes (mefA, ermB, ermTR, linB) and molecular serotyping to determine the genetic characteristics of the strains. Results: Out of 400 samples, 31 (7.75%) were positive for GBS, with 22 (70.97%) showing multidrug resistance. Clindamycin had the highest resistance rate (80.65%), while penicillin showed the lowest (3.23%). Serotypes II and V were the most common (38.71% each), followed by Ia (19.35%) and III (3.23%). The ermB gene was detected in 4 strains, while mefA, ermTR, and linB were not found. Conclusion: Optimal management of GBS infections in pregnant women necessitates ongoing surveillance and antibiotic stewardship, considering penicillin resistance and observed resistance patterns.
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نویسندگان مقاله | Lida Lotfollahi
Department of Microbiology and Virology, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran


| Zahra Shahabi
Department of Microbiology and Virology, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran


| Zahra Mousarezai
Department of Microbiology and Virology, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran


| Shabnam Kimyai
Department of Microbiology and Virology, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran


| Azar Hemmati
Department of Microbiology and Virology, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran


| Ehsan Shojadel
Department of Microbiology and Virology, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran
نشانی اینترنتی https://ijm.tums.ac.ir/index.php/ijm/article/view/5252
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