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International Journal of Hematology-Oncology and Stem Cell Research، جلد ۱۹، شماره ۴، صفحات ۴۲۹-۴۳۳
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عنوان انگلیسی Ulcerated Tongue Borders as a Sign of Amyloidosis in a Patient with Multiple Myeloma
چکیده انگلیسی مقاله Amyloidosis is characterized by extracellular deposition of amyloid material in various tissues and organs. Deposition of amyloid in the tongue is rare but often occurs in multiple myeloma. Here we present the case of a 44-year-old woman under treatment for multiple myeloma who complained of lateral tongue pain. Intraoral examination revealed an ill-defined, firm, whitish swelling with an ulcerated surface on the bilateral borders of the tongue. Histopathological analysis revealed a lympho-mononuclear infiltration in the lamina propria with the presence of acellular and amorphous material positive for Congo red staining. Further examination revealed amyloidosis in a cervical mass associated with neural compression. Thorough examination of the oral cavity in patients with multiple myeloma is critical for early detection of amyloidosis. A biopsy is mandatory to confirm the diagnosis, thereby facilitating intervention and management if necessary.
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نویسندگان مقاله | Osias Vieira de Oliveira-Filho
1) Ceará Oncology and Hematology Center, Fortaleza, CE, Brazil 2)Department of Dentistry, Christus University Center, Fortaleza, CE, Brazil


| Yuri de Lima Medeiros
Department of Stomatology, University of São Paulo, São Paulo, SP, Brazil


| Lorena Dos Santos Girão
Department of Stomatology, University of São Paulo, São Paulo, SP, Brazil


| Igor Campos Guimarães
Department of Public Health, Federal University of Juiz de Fora, Juiz de Fora, MG, Brazil


| Henrique Girão Martins
Ceará Oncology and Hematology Center, Fortaleza, CE, Brazil


| André Costa Teixeira
Medical School, Christus University Center, Fortaleza, CE, Brazil


| Saygo Tomo
Department of Pathology, School of Dentistry, University of São Paulo, São Paulo, SP, Brazil
نشانی اینترنتی https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/2466
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