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Archives of Breast Cancer، جلد ۱۲، شماره ۴، صفحات ۵۰۲-۵۰۵
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عنوان انگلیسی Breast-Predominant Non-Hodgkin Lymphoma Presenting as Infective Mastitis: A Rare Case: Predominant lymphoma mimicking mastitis
چکیده انگلیسی مقاله Background: Primary breast non-Hodgkin lymphoma is an extremely rare malignancy, accounting for only 0.1% to 0.5% of all breast cancers and 1.7% to 2.2% of extranodal lymphomas. Although it has traditionally been defined by the absence of systemic involvement at the time of diagnosis, this strict criterion has been increasingly challenged, as some patients initially present with breast lesions and concurrent systemic disease. In such cases, the term “breast-predominant lymphoma” has been proposed as a more accurate and clinically relevant descriptor. The disease typically manifests as a palpable mass and closely mimics breast carcinoma, making accurate differentiation essential for appropriate management. Case Presentation: We present the case of a 52-year-old woman admitted to the intensive care unit (ICU) with sepsis and an infected breast mass. Laboratory findings revealed hypercalcemia and elevated inflammatory markers. Emergency hemodialysis, empirical antibiotics, and palliative mastectomy were performed. Positron emission tomography–computed tomography (PET-CT) imaging revealed both nodal and extensive extranodal disease. Histopathology confirmed high-grade B-cell lymphoma with BCL2 and MYC rearrangements. No bone marrow involvement was detected. This case was classified as breast-predominant non-Hodgkin lymphoma. Conclusion: This case highlights the importance of a multidisciplinary approach and the role of advanced diagnostics in the management of this rare disease.
کلیدواژه‌های انگلیسی مقاله Lymphoma, diffuse large B-Cell Lymphoma, sepsis, breast neoplasms
نویسندگان مقاله | Dilek Kuzukiran Kocatas
Department of Intensive Care, Ankara Bilkent City Hospital, Ankara, Turkey


| Hulya Ozden Terzi
Department of Intensive Care, Ankara Bilkent City Hospital, Ankara, Turkey


| Burcu Oksuz
Department of Intensive Care, Ankara Bilkent City Hospital, Ankara, Turkey


| Cilem Bayindir Dicle
Department of Intensive Care, Ankara Bilkent City Hospital, Ankara, Turkey


| Irem Sahin
Department of Internal Medicine, Ankara Bilkent City Hospital, Ankara, Turkey


| Nermin Damla Hatipoglu Okay
Department of General Surgery, Ankara Bilkent City Hospital, Ankara, Turkey


| Dilek Kazanci
Department of Intensive Care, Ankara Bilkent City Hospital, Ankara, Turkey
نشانی اینترنتی https://archbreastcancer.com/index.php/abc/article/view/1131
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi) 10.32768/abc.6782051397-406
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده Case Report
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