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Journal of Medicinal Plants and By-products، جلد ۱۴، شماره ۵، صفحات ۴۸۹-۴۹۷
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عنوان انگلیسی Efficacy of Ferula gummosa Essential Oil in an Anti-Acne Cream: Evaluation of Antibacterial Activity, Sebum Reduction, and Sensory Properties
چکیده انگلیسی مقاله Acne vulgaris is a prevalent skin condition affecting adolescents and young adults, with conventional treatments often leading to undesirable side effects. This study developed the formulation of an anti-acne cream based on Ferula gummosa essential oil and evaluated its physicochemical properties, antibacterial efficacy, and effects on sebum production. The formulated cream demonstrated favorable physicochemical properties, making it suitable for skin application. It exhibited strong antibacterial activity against both Propionibacterium acnes and Staphylococcus epidermidis. Significant reductions in sebum levels were observed in all areas of the face studied at the end of the trial. Participants rated the cream highly on several quality dimensions, although improvements in fragrance were suggested. The anti-acne cream containing galbanum essential oil shows significant potential in the treatment of acne vulgaris, combining effective sebum reduction and antibacterial activity with favorable user acceptability. This study supports further development and clinical testing of F. gummosa based formulations as a natural and effective treatment option for acne.
کلیدواژه‌های انگلیسی مقاله Acne vulgaris,Galbanum based cream,Propionibacterium acnes,Sebum
نویسندگان مقاله Arefeh Vaez Shahrestani |
Department of Horticultural Science and Agronomy, Science and Research Branch, Islamic Azad University, Tehran, Iran

Razieh Azimi |
Research Institute of Forests and Rangelands, Agricultural Research Education and Extension Organization (AREEO), Tehran, Iran

Vahid Abdossi |
Department of Horticultural Science and Agronomy, Science and Research Branch, Islamic Azad University, Tehran, Iran

Mehdi Mirza |
Research Institute of Forests and Rangelands, Agricultural Research Education and Extension Organization (AREEO), Tehran, Iran

Marzieh Ghanbari Jahromi |
Department of Horticulture Science and Agronomy, Science and Research branch of Islamic Azad University, Tehran, Iran

نشانی اینترنتی https://jmpb.areeo.ac.ir/article_133277_57ef6689e10f1989b113163a67074206.pdf
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