این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Iranian Journal of Public Health، جلد ۵۴، شماره ۱۱، صفحات ۲۵۰۸-۲۵۲۰
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی The Association between Dairy Consumption and the Risk of Developing Multiple Sclerosis: A Systematic Review and Meta-Analysis
چکیده انگلیسی مقاله Background: Multiple sclerosis (MS) is a chronic and disabling disease that commonly affects young adults. We aimed to provide a comprehensive review of the current literature on the association between dairy consumption, particularly cow milk, and the risk of developing MS. Methods: This systematic review and meta-analysis was conducted in accordance with PRISMA guidelines. We searched PubMed, Web of Science, Cochrane Library, and Scopus for peer-reviewed papers published until 2024. Eligible studies included randomized controlled trials, quasi-experimental studies, and observational designs (case-control, cohort, cross-sectional). Studies were excluded if they did not report sufficient data to calculate effect sizes. Study quality was assessed using the Newcastle-Ottawa Scale (NOS). A random-effects meta-analysis was conducted, and heterogeneity was assessed using the I² statistic. Results: Twenty studies met the inclusion criteria. The overall pooled odds ratio (OR) for the association between total dairy consumption and MS risk was 0.96 (95% CI: 0.93–0.99), indicating a weak but statistically significant inverse association. Subgroup analysis of cohort studies, however, showed no significant association (relative risk [RR] = 1.18, 95% CI: 0.95–1.47, P = 0.41). Furthermore, cow's milk consumption alone was not significantly associated with MS development (OR = 0.88, 95% CI: 0.46–1.69, P = 0.21). Conclusion: Although pooled results suggest a slight protective effect of overall dairy consumption on MS risk, findings remain inconsistent and inconclusive, especially when considering specific dairy products and study design. Additional longitudinal studies with rigorous methodology are needed to clarify the potential role of dairy in MS pathogenesis.
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله | Behnaz Sedighi
Neurology Research Center, Kerman University of Medical Sciences, Kerman, Iran


| Simin Jafari
Neurology Research Center, Kerman University of Medical Sciences, Kerman, Iran


| Shoboo Rahmati
Social Determinants of Health Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran


| Fatemeh Ajam
Department of Biostatistics and Epidemiology, Faculty of Public Health. Kerman University of Medical Sciences, Kerman, Iran


| Seyedeh Tahereh Afrah
Department of Biostatistics and Epidemiology, Faculty of Public Health. Kerman University of Medical Sciences, Kerman, Iran


| Simin Salehinejad
Research Center of Tropical and Infectious Diseases, Kerman University of Medical Sciences, Kerman, Iran


| Mahdieh Mirzaie
Department of Biostatistics and Epidemiology, Faculty of Public Health. Kerman University of Medical Sciences, Kerman, Iran


| Roya Amir Gooshki
Faculty of Medicine, Kerman University of Medical Sciences, Kerman, Iran


| Parya Jangipour Afshar
HIV/STI Surveillance Research Center, and WHO Collaborating Center for HIV Surveillance, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran
نشانی اینترنتی https://ijph.tums.ac.ir/index.php/ijph/article/view/37846
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات