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International Journal of Fertility and Sterility، جلد ۶، شماره ۳، صفحات ۱۷۵-۱۷۸
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عنوان انگلیسی Effect of Adding Human Chorionic Gonadotropin to The Endometrial Preparation Protocol in Frozen Embryo Transfer Cycles
چکیده انگلیسی مقاله < p>Background: Human chorionic gonadotropin (HCG), one of the initial embryonic signals, is probably a major regulator of the embryo-endometrial relationship. This study aims to assess the advantage of HCG supplementation during the secretory phase of hormonally prepared cycles for the transfer of cryopreserved-thawed embryos. Materials and Methods: This study was a randomized clinical trial. Infertile women who were candidates for frozen-thawed embryo transfers entered the study and were divided into two groups, HCG and control. The endometrial preparation method was similar in both groups: all women received estradiol valerate (6 mg) po per day from the second day of the menstrual cycle and progesterone in oil (100 mg) intramuscular (I.M.) when the endometrial thickness reached 8 mm. Estradiol and progesterone were continued until the tenth week of gestation. In the HCG group, patients received an HCG 5000 IU injection on the first day of progesterone administration and the day of embryo transfer. Results: In this study, 130 couples participated: 65 in the HCG group and 65 in the control group. There was no statistically significant difference between groups regarding basic characteristics. Implantation rate, chemical pregnancy, clinical pregnancy, ongoing pregnancy, and abortion rates were similar in both groups. Conclusion: Although HCG has some advantages in assisted reproductive technology (ART) cycles, our study did not show any benefit of HCG supplementation during the secretory phase of frozen cycles (Registration Number: IRCT201107266420N4).
کلیدواژه‌های انگلیسی مقاله art, implantation, Frozen Embryo, hCG
نویسندگان مقاله Maryam Eftekhar |
Department of Obstetrics and Gynecology, Yazd Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

Elham Rahmani |
Department of Obstetrics and Gynecology, Bushehr University of Medical Sciences, Bushehr, Iran

Tahereh Eftekhar |
Department of Obstetrics and Gynecology, Tehran University of Medical Sciences, Tehran, Iran

نشانی اینترنتی https://www.ijfs.ir/article_45141_8a49a33008bf11df4ff5f6c52d6ba517.pdf
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