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Cell Journal، جلد ۱۶، شماره Suppl ۱، صفحات ۹۸-۹۸
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عنوان انگلیسی Ps-66: Survey of Interaction between Induced Pluripotent Stem Cells and PLA/ Gelatin Scaffold
چکیده انگلیسی مقاله Objective: Today, induced pluripotent stem cells (iPSCs) have been recognized as a new and good cell source for cell therapy. In recent years, research in the field of cell therapy and tissue engineering is widely developed and today there is a potential for the preparation of various types of scaffolds for different cells. In this study, in order to increase surface adhesion properties and cell survival, nanofiber scaffold polylactic acid was modified by using suitable concentration of gelatin. Materials and Methods: Different scaffolds were fabricated by an electro spinning technique and cells morphology and cells viability were evaluated by using a scanning electron microscopy and MTT assay, respectively. Results: The results of this study demonstrated that the modified PLA/gelatin scaffold is a more appropriate model for the adhesion, proliferation and survival of iPS cells. PLA/gelatin scaffold significantly increases cell attention and cell survival. Conclusion: These findings are an important step in the use of appropriate three dimensional culture in order to treat a variety of diseases.
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نشانی اینترنتی http://celljournal.org/journal/article/abstract/392
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