این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Cell Journal، جلد ۱۵، شماره Suppl ۱، صفحات ۴۷-۴۷
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Ps-63: Comparison of The Growth Curves of Mesenchymal Stem Cells Isolated from Third Molar and First Premolar Human Dental Pulp
چکیده انگلیسی مقاله Objective: Based on previous researches, dental pulp stem cells (DPSCs) were primarily derived from the pulp tissues of permanent third molar teeth. Their embryonic origin, from neural crests, explains their multipotency. These cells are easily accessible with limited morbidity after collection. This study was undertaken to compare the growth curves of mesenchymal stem cells isolated from third molar and first premolar human dental pulp. Materials and Methods: To obtain DPSCs, pulp tissues were isolated from human third molar and first premolar teeth. They were digested by treating with collagenase type I. The extracted cells were passaged from primary culture up to passage 8. To enumerate the cells, the specified number of the cells was seeded into 24-well culture plates and the number of colonies was counted to determine the growth curves of isolated cells from both types of teeth. Results: The human DPSCs from both third molar and first premolar teeth were spindle-shaped in morphology. As growth curves show, the proliferation rate of DPSCs in 8th passage among both teeth was different denoting to an increase in doubling time in 3rd molar when compared to 1st premolar teeth. Conclusion: DPSCs can be an attractive candidate in regenerative medicine. As growth curves show, 3rd molar tooth is suggested as a better source of MSC isolation
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله
نشانی اینترنتی http://celljournal.org/journal/article/abstract/867
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات