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Cell Journal، جلد ۱۵، شماره Suppl ۱، صفحات ۶۹-۶۹
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عنوان انگلیسی Ps-112: The Pluripotency Properties of Human Placenta-Derived Mesenchymal Stem Cells
چکیده انگلیسی مقاله Objective: The placenta is a complex, sophisticated organ with several important functions throughout gestation. To explore the feasibility of placenta tissue as a reliable and efficient source for generating mesenchymal stem cells (MSc) we studied some of pluripotency properties in these cells. Materials and Methods: MSC were generated from human placenta tissue by explant. The cells at third passage were characterized for expression of cell surface markers. Placenta derived MSCs was stained with a panel of monoclonal antibodies: CD90, CD44, CD105,CD34 and CD133.Stained cells were re-suspended in PBS, analyzed using FACS Calibur flow cytometer . Results: Flow cytometry analyses showed that MSCs was a homogeneous cell population, which more than 90% of the cells were positive for mesenchymal markers (CD90, CD44, CD105), and negative for CD34 and CD133. Conclusion: This study showed that human MSCs were positive for mesenchymal markers, this data indicating their closeness with embryonic stem cells and they are a good novel source for stem cell therapy
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نشانی اینترنتی http://celljournal.org/journal/article/abstract/916
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