این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Cell Journal، جلد ۱۳، شماره Supplement، صفحات ۰-۰
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی P-13: Expressional Correlation of HumanEpidermal Growth Factor Receptor 2, Estrogen/ Progesterone Receptor and Protein 53 in Breast Cancer
چکیده انگلیسی مقاله Objective: Breast cancer comprises a remarkably diverse group of diseases which affects Iranian women at least one decade younger than their counterparts in developed countries. This study shows localization of Estrogen / Progesterone Receptor, human epidermal growth factor receptor 2 (Her-2) and protein 53 (P53) by Immuno-histochemistry methods in consecutive breast cancer patients. Materials and Methods: The study includes invasive breast cancers from 299 patients who submitted to the Oncogenetic Clinic and Pathology Centers of Ahwaz Jondishapour University of Medical Sciences Hospital in Iran during time period from 2005 to 2007. The Scarff-Bloom Richardson scoring method has been used in this study. Differences at p< 0.05 were considered as statistically significant. Results: Of these 299, 27% (80/299) were < 40, 33% (100/299) were 41-50, and the rest 40% (119/299) had >50 years old. The highest incidence of breast cancer in this study population was in the group of more than 50 year age, and the most common histological type of breast cancer was the invasive ductal carcinoma, which accounted for 68% (203/299) of the cases. Out of total 207, 6% (13/207), 41% (85/207), and 53% (109/207) were scored as grade І, ІІ, ІІІ, respectively. Conclusion: These conflicting results may be due to difference in the immunohistochemical techniques applied in the various studies and to the scoring systems used. Our findings also confirm lack of association between labeling for the markers studied and tumor size and age of the patients. We have confirmed the association between ER labeling and nuclear grade of breast cancer.
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله
نشانی اینترنتی http://celljournal.org/journal/article/abstract/1545
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات