این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Cell Journal، جلد ۱۳، شماره Supplement، صفحات ۰-۰
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی P-56: Evaluation of Hyperglycemia Effect on Circulating Immunoglobulin Levels and Complement Activity. Are Diabetic Patients Susceptible to Infections?
چکیده انگلیسی مقاله Objective: It has been widely thought that diabetic patients are prone to infections due to hyperglycemia induced immunodeficiency. We here present some evidence criticizing this belief. Materials and Methods: For all the diabetic and normal subjects enrolled in this study, by single radial immunodiffiusion(SRID), total serum immunoglobulins (IgG,IgA,IgM), C3, C4 and CH50 were determined to evaluate humoral immunity. Results: The mean serum concentration of IgA in diabetic patients was 245.86 ± 115.05 mg/dl versus192.96 ± 105.33 mg/dl in healthy control group (p< 0.018). The mean ±SD serum concentrations of IgG (2540.82 ± 1528.62)and IgM (305.54 ± 121.66) in diabetic patients were lower than the control subjects (IgG; 3035.76 ± 1588.01, IgM; 323.58 ± 110.78). These differences were not statistically significant. Diabetic patients had higher levels of serum C3 and C4 when compared with healthy control subjects; in diabetic group, the mean ± SD concentration of C3 and C4 were 101.68 ± 4.31 mg/dl, 43.12 ± 3.51 mg/dl and in normal control group, the values were 93.12 ± 3.67, 38.46 ± 2.51, respectively. However, these differences were not statistically significant. Also, between the two groups there was no significant difference in CH50 activity. Conclusion: The data generated by this present study demonstrates that in non-complicated diabetic patients, there is no substantial mitigation in both arms of humoral immunity and a common belief that patients with diabetes are prone to infections that may require revision. with diabetes are prone to infections that may require revision.
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله
نشانی اینترنتی http://celljournal.org/journal/article/abstract/1588
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات