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International Journal of Fertility and Sterility، جلد ۱۰، شماره ۲، صفحات ۱۶۲-۱۶۸

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عنوان انگلیسی Comparison of Risk of Preterm Labor between Vaginal Progesterone and17-Alpha-Hydroxy-Progesterone Caproate in Women with Threatened Abortion: A Randomized Clinical Trial
چکیده انگلیسی مقاله Objective: Threatened miscarriage is a common complication in pregnancy that leads to adverse pregnancy outcomes such as preterm labor. This study aimed to compare the vaginal progesterone (Cyclogest) versus 17-alpha-hydroxyprogesterone caproate (Proluton) on preventing preterm labor in pregnant women with threatened abortion at less than 34 weeks’ gestational age. Materials and methods: This balanced randomized, double-blind, single-center controlled clinical trial included 190 women with threatened abortion. They were then randomly allocated into Cyclogest (n=95) and 17-alpha-hydroxyprogesterone caproate (Proluton, n=95) groups. Interested outcome was preterm labor less than 34 weeks. The Pearson chi-square and Student’s t test were used to compare two groups. The data were analyzed by Stata software version 13. Results: The risks of preterm labor less than 34 weeks in Proluton and Cyclogest groups were 8.6 and 6.52%, respectively. There was no significant difference for risk of preterm labor less than 34 weeks [relative ratio (RR): 1.31, 95% confidence interval (CI): 0.47- 3.66, P=0.59] between two groups. Conclusion: Risk of preterm labor in the vaginal progesterone group and 17-alpha-hydroxyprogesterone caproate group in pregnant women with threatened abortion is the same (Registration Number: IRCT2014123120504N1).
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نویسندگان مقاله ابوطالب بیگی | abootaleb beigi


آرزو اسماعیل زاده | arezoo esmailzadeh


ریحانه پیرجانی | reyhane pirjani



نشانی اینترنتی http://ijfs.ir/journal/article/abstract/4905
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/72/article-72-367983.pdf
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