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International Journal of Fertility and Sterility، جلد ۹، شماره ۲، صفحات ۱۷۶-۱۸۲
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عنوان انگلیسی Association of Glomerular Filtration Rate with Inflammation in Polycystic Ovary Syndrome
چکیده انگلیسی مقاله Background: We aimed to estimate the glomerular filtration rate (GFR) in women with polycystic ovary syndrome (PCOS) and to determine the relationship between GFR with C-reactive protein (CRP) and uric acid. Materials and methods: In this cross-sectional study, one-hundred and forty PCOS women and 60 healthy subjects were evaluated. The study was carried out at Endocrinology Outpatient Clinic, Erzurum Training and Research Hospital, Erzurum, Turkey, from December 2010 to January 2011. GFRs were estimated by Modification of Diet in Renal Disease (MDRD) formula. CRP, urinary albumin excretion (UAE) and uric acid levels were also measured. Results: GFRs were significantly higher in PCOS group than control (135.24 ± 25.62 vs. 114.92 ± 24.07 ml/min per 1.73 m2). CRP levels were significantly higher in PCOS patients (4.4 ± 3.4 vs. 2.12 ± 1.5 mg/l). The PCOS group had significantly higher serum uric acid levels (4.36 ± 1.3 mg/dl vs. 3.2 ± 0.73 mg/dl). There was also significantly higher proteinuria level in PCOS patients. Conclusion: Even though PCOS patients had higher GFR, serum uric acid and UAE values than control patients, the renal function was within normal limits. Increased GFR in PCOS women positively correlates with elevated serum CRP and uric acid.
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نویسندگان مقاله ilay ozturk gozukara | ilay ozturk gozukara


kerem هانیه gozukara | kerem han gozukara


suna kabil kucur | suna kabil kucur


eda ulku karakılıc | eda ulku karakılıc


حوا keskin | havva keskin


دریا akdeniz | derya akdeniz


آیسه نور aksoy | ayse nur aksoy


آیسه carlıoglu | ayse carlıoglu


نشانی اینترنتی http://ijfs.ir/journal/article/abstract/4238
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/72/article-72-368686.pdf
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