این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Cell Journal، جلد ۷، شماره ۲، صفحات ۵۶-۶۱
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Effect of DEHP (Di-2-Ethyl Hexyl-Phthalate) on Resumption of Meiosis and in-vitro Maturation of Mouse Oocytes and Development of Resulting Embryos
چکیده انگلیسی مقاله Introduction: DEHP [di(2-ethylhexyl) phthalate)] is widely used in plastic industry and some reproductive toxicity has been shown with it. So, this study was designed to evaluate DEHP effects on resumption of meiosis and in vitro maturation of mouse oocytes as well as development of embryos resulted from them. Material and Methods: Mice of 4-6 weeks old were administered daily doses of 50, 100, 200 µl of 2.56 µM DEHP solution for 12 days. Immature mouse oocytes were recovered from all experimental groups and matured in MEM-α medium containing 5% FCS with and without 7.5 IU hCG and 100 mIU rFSH. IVF was performed T6 medium. Results: Resumption of meiosis and in vitro maturation were significantly lower in all experimental groups in culture media without hormones compared to controls. Fertilization and embryo development were also significantly decreased in both culture media (with and without hormones). Conclusions: This study showed the adverse effects of DEHP on in vitro maturation and embryo development in a dose dependent manner.
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله
نشانی اینترنتی http://celljournal.org/journal/article/abstract/3479
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/16/article-16-368691.pdf
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات