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JCR 2016
جستجوی مقالات
جمعه 28 آذر 1404
International Journal of Fertility and Sterility
، جلد ۹، شماره ۱، صفحات ۱۲۱-۱۲۸
عنوان فارسی
چکیده فارسی مقاله
کلیدواژههای فارسی مقاله
عنوان انگلیسی
Oxidant and Antioxidant Status in Experimental Rat Testis after Testicular Torsion/Detorsion
چکیده انگلیسی مقاله
Background: The aim of this study was to determine oxidative stress (OS) parameters after testicular torsion/detorsion in adult rats. Materials and methods: In this experimental study, male adult Wistar rats were divided into four groups, each consisting of seven animals: group I-one hour right testicular torsion with subsequent orchiectomy, group II-one hour right testicular torsion followed by detorsion, group III-unilateral right-sided orchiectomy without previous torsion and group IV-control. After 30 days, bilateral orchiectomies were performed in rats with both testes and unilateral orchiectomies in rats with single testicles. Parameters of OS were determined in testicular tissue and in plasma. Results: Plasma concentrations of advanced oxidation protein products (AOPP) and thiobarbituric acid reactive substances (TBARS) were higher (p< 0.05 and p< 0.01, respectively), whilst the plasma concentration of the total sulfhydryl (T-SH)-groups was lower (p< 0.05) in group I compared to the control group. Group II had higher plasma concentrations of AOPP compared to group IV (p< 0.05), as well as significantly increased TBARS and decreased T-SH-group levels compared to groups III (p< 0.05 and p< 0.01, respectively) and IV (p< 0.01, for both parameters). There were significant differences in OS markers between the ipsilateral and contralateral testis, as well as significant correlations among levels of both plasma and tissue markers of OS. Conclusion: The increase in TBARS levels seen throughout the experimental period indicated that OS development was caused by ischemia/reperfusion in the testicular tissue. The oxidant-antioxidant system of the testicular tissue was altered during torsion as well as detorsion.
کلیدواژههای انگلیسی مقاله
نویسندگان مقاله
tatjana cvetkovic | tatjana cvetkovic
jablan stankovic | jablan stankovic
stevo najman | stevo najman
dusica pavlovic | dusica pavlovic
dragana stokanovic | dragana stokanovic
slobodan vlajkovic | slobodan vlajkovic
marija dakovic bjelakovic | marija dakovic bjelakovic
jovana cukuranovic | jovana cukuranovic
ولادیمیر zivkovic | vladimir zivkovic
vladisav stefanovic | vladisav stefanovic
نشانی اینترنتی
http://ijfs.ir/journal/article/abstract/4216
فایل مقاله
اشکال در دسترسی به فایل - ./files/site1/rds_journals/72/article-72-368735.pdf
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زبان مقاله منتشر شده
en
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