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International Journal of Fertility and Sterility، جلد ۸، شماره ۲.۵، صفحات ۴-۴
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عنوان انگلیسی I-9: Sperm Trans Fatty Acids: An Undertreated Issue in Men Infertility
چکیده انگلیسی مقاله Background: Mammalian spermatozoa are characterized by a high proportion of polyunsaturated fatty acids (PUFA) and the membrane structure of spermatozoa plays a crucial role in fertilization. Moreover, dietary fatty acid (FA) influence sperm FA profiles in several species. This study focused on responses to dietary omega-3 fatty acids and comprehensive fatty acid profiles analysis in men as well as trans fatty acids in previous studies in ruminant and human. Materials and Methods: Sperm FA profiles of human and ruminants consists of: C22:6n-3 (docosahexaenoic acid: DHA) is the predominant PUFA and C16:0 (palmitic acid) is the predominant saturated FA in the sperm of these species. Sperm structure is associated with sperm movement and acrosome reaction. Whether the higher levels of DHA are concentrated in the sperm head or tail is variable among different species. There is a striking similarity between humans and ruminants whose sperm head contain higherconcentration of DHA. Results: Dietary FA influence sperm FA profiles in human and ruminants. Improvements in sperm parameters are a typical response to fish oil after more than four weeks of supplementation in diets. Tarns fatty acids are a missing link in biological systems such as sperm. Conclusion: It appears that regulation of sperm FA mean melting point (MMP) is the key factor causing responses by dietary manipulation. Interestingly, some hypotheses which explain milk fat depression (MFD) in dairy cattle by dietary fatty acids seem to be applicable and sperm fat depression (SFD) may be suggested in infertile men.
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نشانی اینترنتی http://ijfs.ir/journal/article/abstract/3795
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