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International Journal of Fertility and Sterility، جلد ۸، شماره ۲.۵، صفحات ۱۱۸-۱۱۸
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عنوان انگلیسی P-105: Prenatal Effects Exposure to Extremely Low Frequency- Electromagnetic Field (ELF-EMF) on Pathology of Testis in Newborn Rats
چکیده انگلیسی مقاله Background: Human beings are unavoidably exposed to ambient electromagnetic fields (EMF) generated from various electrical devices and from power transmission lines. The effects of extremely low-frequency electromagnetic fields (ELF-EMF) on the biological functions of living organisms represent an emerging area of interest for human health. One of the critical issues is that EMF may adversely affect the reproductive system. The aim of this work is to evaluate the effects of intrauterine exposure to 50Hz electromagnetic field (ELF-EMF) on testicular development. Materials and Methods: Pregnant wistar rats were exposed to 3mT, EMF for 21 days (4 hours/day). Pregnant rats under the same condition of treatment group, but off the field as a Sham group intended and pregnant rats were used as control in the room. After delivery, testis were removed from male pups, fixed and prepared for light microscopic studies. Results: Microscopic results revealed seminiferous tubules in treatment group were widely separated from each other, in this group in seminiferous tubules vacuolization, detachment of gonocytes from each other, heterochromatic gonocytes and decreasing in interstitial tissue in comparison with the control and sham groups was found. In sham and control groups the seminiferous tubules and interstitial tissue appeared normal. Conclusion: Early pregnancy exposure to magnetic field affects gonads in prenatal male fetuses and postnatal testicular development. EMF can influence the mechanism of apoptosis and also lead to increased apoptosis rate of germ cells. In general, as a result of the exposure to EMF during early developmental period, morphological changes in testicular development were evident that may well extend till adult stage and may affect fertility.
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نشانی اینترنتی http://ijfs.ir/journal/article/abstract/3968
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