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International Journal of Fertility and Sterility، جلد ۸، شماره ۲.۵، صفحات ۲۰۳-۲۰۳
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عنوان انگلیسی P-192: Evaluation The Effect of Intrauterine Human Chorionic Gonadotropin Injection before Embryo Transfer in Implantation and Pregnancy Rate in Infertile Patients and Comparison with Conventional Embryo Transfer in IVF/ICSI/ Embryo Transfer Cycles: A Randomized Clinical Trial
چکیده انگلیسی مقاله Background: Implantation is one of the key stages for the success of assisted reproductive techniques (ART). The complex process of Implantation is regulated by various factors which one the most important of them is human chorionic gonadotropin (HCG). This prospective, randomized clinical study aimed to investigate the effect of intrauterine HCG injection before Embryo Transfer (ET) on pregnancy outcome in infertile couples. Materials and Methods: We evaluated 159 patients undergoing Invitro Fertilization/Intracytoplasmic Sperm Injection (IVF/ ICSI) with antagonist protocol from 317 patients candidates for IVF/ ICSI. The patients divided into three groups by a computer-based program. Case group I (n=53) received 500 IU of HCG and case group II, (n=53) received 1000 IU of HCG intrauterine injection before ET, and control group undergoing ET without a preceding intrauterine injection of HCG. Results: There was no significant difference between case group I, II and control group.The implantation rates were 18.86, 13.52, 14.37% respectively, chemical pregnancy rates were 34, 32.15, 35.3% respectively, and clinical pregnancy rates were 32.1, 32.1, 31.4% respectively. Conclusion: Intrauterine injection of HCG before ET does not improved the pregnancy outcomes in IVF/ICSI /ET cycles.
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نشانی اینترنتی http://ijfs.ir/journal/article/abstract/4056
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