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International Journal of Fertility and Sterility، جلد ۷، شماره ۳، صفحات ۹۹-۹۹
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عنوان انگلیسی P-166: Obstetric and Neonatal Outcomes of Twin Pregnancies Conceived by Assisted Reproductive Techniques Compared with Natural Conceived Twins: A Prospective Follow-Up Study
چکیده انگلیسی مقاله Background: Comparison of obstetric and neonatal outcomes of twin pregnancies conceived by assisted reproduction technology (ART) with those of spontaneously conceived (SC). Materials and Methods: In this prospective cohort study, all dichorionic twin pregnancies following fresh IVF/ intra-cytoplasmic sperm injection (ICSI) or ICSI cycles (n=320) and (SC) (n=170) in nulliparous women in Royan Institute with those conceived spontaneously in Arash Women’s hospital (university-based hospital) were evaluated from January 2008 to October 2010 and followed up until delivery. We compared the obstetric and neonatal outcomes of SC and ART twin pregnancies. Results: Multivariable analysis, adjusted for maternal age and body mass index, revealed the obstetrics outcomes were similar between groups but in ART group, neonatal outcome was associated with a higher risk of very preterm birth (odds ratio (OR): 5.2, confidence interval (CI):2.1-12.9), extreme low birth weight (OR: 2.2, CI: 1.0-3.9), neonatal intensive care unit admission (OR: 2.0, CI: 1.2-3.2) and perinatal mortality (OR: 2.3, CI: 1.2- 4.0). Conclusion: The maternal outcomes of ART dichorionic twins are comparable to those of spontaneously conceived; despite of attempting to perform the same obstetric management, the rates of very preterm birth, Extreme low birth weight, neonatal intensive care unit admission and perinatal mortality were significantly higher in the ART group.
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نشانی اینترنتی http://ijfs.ir/journal/article/abstract/3627
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