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International Journal of Fertility and Sterility، جلد ۷، شماره ۳، صفحات ۱۰۸-۱۰۸
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عنوان انگلیسی P-182: The Comparison of Clinical and Laboratory Characteristics in Obese and Normal Weight Women with Polycystic Ovary Syndrome
چکیده انگلیسی مقاله Background: The main characteristic of polycystic ovary syndrome (PCOS) is oligomenorrhea with clinical and biochemical signs of hyperandrogenism(HA) and the phenotypic spectrum of PCOS is very broad. There are very limited studies about the features of patients with PCOS in Iran. The purpose of this study is to compare the clinical and laboratory characteristics of PCOS between the overweight women and normal. Materials and Methods: In this cross sectional study with control group, 368 patients with PCOS, aged 15-39 year, were investigated PCOS was diagnosed by Rotterdam criteria. The patients were divided in two groups [with body mass index (BMI) ≥25 and with BMI < 25]. The demographic, clinical, biochemical and sonographic features of patients were registered in the questionnaires, then four presented phenotypes were determined by rotterdam criteria [irregular menes (IM)/PCO/HA, IM/PCO, IM/HA, PCO/HA]. Data were analyzed by statistical software of SPSS. Results: The most common phenotype in both groups was IM/HA/PCO (54.89%) and the most common clinical signs were oligomenorrhea (81.2%) and hirsutism (65.67%). Differences between overweight and normal weight groups for hirsutism, irregular means, Galactorrhea, acne, alopecia, living place, family history of DM, acanthosis nigricans, polycystic ovary, the volume of ovary, testosterone, DHEAS, and the phenotypes of PCOS. In over weight group, the mean age (26.8 vs. 25.59. PV:0), the mean systolic blood pressure (114.4 vs. 106.66. PV: 0.01) the mean diastolic blood pressure (73.24 vs. 67.29, PV: 0.01), the prevalence of infertility (45.5% vs. 22.61% PV: 0) and the prevalence of android obesity (PV:0) were significantly higher than normal weight group. Conclusion: In over weight group, the prevalence of infertility and android obesity and mean of age and SBP and DBP, were significantly higher than normal weight group.
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نشانی اینترنتی http://ijfs.ir/journal/article/abstract/3643
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