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International Journal of Fertility and Sterility، جلد ۷، شماره ۳، صفحات ۱۲۴-۱۲۴
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عنوان انگلیسی Inm-2: Polycystic Ovarian Syndrome is a Potent Risk Factor for GDM in Infertile Patient
چکیده انگلیسی مقاله Objective: Gestational diabetes mellitus (GDM), a common medical complication of pregnancy, is defined as “any degree of glucose intolerance with onset or first recognition during pregnancy.Risk factors for GDM: a previous GDM or Pre diabetes , a family history revealing a first degree relative with type 2 diabetes , maternal age (>35yr), ethnic background , being overweight , a previous pregnancy which resulted in a child with a high birth weight , Poly cystic ovary syndrome (PCOS). The aim of this study is influence of PCOS on GDM without consideration of obesity. Materials and Methods: Our retrospective study subjects were530 patients with different Diagnosis of infertility who offered to prenatal Clinic after pregnancy with assisted reproductive technique (ART) in Royan Institute during 12month(March2012-February2013).Diagnosis of PCOS patients has been with Roterdom criteria . Diagnosis of GDM was based on glucose challenge test (GCT) (with 50 gr Glucose) and then confirmed with glucose tolerance test (GTT) (with 100 gr Glucose) in 24-28 week of pregnancy. Weight and Height were measured and body mass index (BMI) was calculated for each patient .The prevalence of GDM in PCOS and non PCOS were compared. Result: Mean age: 29.8±4.5, Mean BMI: 25.2±3.9.Total number of patient were 530, 204 and 326 were PCOS and Non PCOS respectively.100 of 204 patients with PCOS had GDM (49.4%) and 111 of 326 patients with non PCOS had GDM (34%), it shows that prevalence of GDM were significantly higher in PCOS subjects. (P=0.001) Mean BMI and age were (BMI: 26.1 ± 3.5, Age: 29.8 ± 4.1) in PCOS and (BMI: 25.5 ± 4.1, Age: 30.9 ± 4.8) in Non PCOS woman respectively. There were no statistically significant differences in BMI and age factors between two groups. Conclusion: PCOS is one of the most important risk factors for GDM without consideration of obesity. We recommend infertile patients with history of PCOS should be investigated for GDM as soon as possible in pregnancy.
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نشانی اینترنتی http://ijfs.ir/journal/article/abstract/3690
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