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International Journal of Fertility and Sterility، جلد ۷، شماره ۳، صفحات ۱۲۶-۱۲۶
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عنوان انگلیسی Inm-9: Cord Blood Banks and Cord Blood Donors Selection
چکیده انگلیسی مقاله Cord blood is a sample of blood taken from a newborn baby's umbilical cord.Cord blood is collected because it is rich in stem cells content, such as hematopoietic cells, which can be used to treat hematopoietic and genetic disorders. Cord Blood Transplantation has been used in the treatment of over 80 diseases, including leukemia, lymphoma and anemia. Advantages of Cord Blood Treatment: • Ease of collection • No risk for mother or child • Less time needed for processing (more quickly available for use) • Less risk for transmission of infection • Less need for stringent antigen matching • Less rejection Disadvantages of Cord Blood Treatment: • Slow engraftment • Limited cell dose as a result of small volume of unit and additional cell doses unavailable • Autologous donation may have limited benefit due to hereditary disorders A cord blood bank is a facility which stores umbilicalcord blood for future use andcould befamilial (private)or public. Public banks accept donations to be used for anyone in need, whereas, private banks register the identity of donors, so that the donors’ families may retrieve the samplesin the future.There are 4cord blood banks in Iran: 1. Royan institute Private cord blood bank 2. Royan institute Public cord blood bank 3. National cord blood bank of Iranian blood transfusion organization 4. Shariati hospital cord blood bank Cord Blood Donor Selection: The donors must be evaluated for the suitability of their infant’s cord blood for donation based on their medical history (Former and current diseases),drug history,maternal tests (RPR, HBsAg, HBsAb, HBcAb, HCVAb, HIV (I, II), HTLV (I, II), CMV (IgM, IgG)), and etc. They are selected in advance to ensure that their baby’s cord blood stem cells are unlikely to harm any recipients.
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نشانی اینترنتی http://ijfs.ir/journal/article/abstract/3697
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