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مجله علوم اعصاب شفای خاتم، جلد ۵، شماره ۲، صفحات ۸۹-۸۹
عنوان فارسی P ۵۸: Herbal Medicine “Ginseng” as Therapy and Prevention of Parkinson`s Disease
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عنوان انگلیسی P 58: Herbal Medicine “Ginseng” as Therapy and Prevention of Parkinson`s Disease
چکیده انگلیسی مقاله Parkinson`s disease (PD) is the second most common neurodegenerative disorder after Alzheimer`s disease. It is a chronic and progressive disease, and mostly afflicts elderlies. PD starts with sudden onsets and the exact cause of the disease is still unknown, however there are some early symptoms that can help us to diagnose the disease and ameliorate its effects. PD is a multi-factorial disease, so finding a certain cure is difficult, but recent studies about the role of neuroinflammation and oxidative stress in PD has opened a new window. In fact, in PD inflamed microglias produce the free radical "nitrogen monoxide" which causes neurodegeneration, and neurodegeneration in Substatia Nigara reduces the secretion of dopamine which results in motor symptoms of the disease. These findings clarify that anti-oxidants and anti-inflammatory mechanisms can be very helpful in the PD treatment. Recent research about prevention or reduction of the  effects of PD using herbal anti-oxidant medications are promising.one of the herbal medications thought to be effective in PD is Ginseng extract. Studies show significant ant-inflammatory effects of Ginseng which can prevent formation of inflamed microglias at the first stage, also Ginseng changes antioxidant enzymes activity and nitric acid production resulting in restriction of free radicals and controlling oxidative stress. Based on these facts Ginseng is a suggested neuroprotective therapy for PD, but of course using it as an accepted therapy needs enough trials with reassuring results.
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نویسندگان مقاله آناهیتا قزاقی | anahita ghazaghi
a. islamic azad university, mashhad branch, mashhad, iran b. members of mashhad neuroscience research group of islamic azad university, mashhad branch, mashhad, iran

سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)

علی ابراهیمی | ali ebrahimi
a. islamic azad university, mashhad branch, mashhad, iran b. members of mashhad neuroscience research group of islamic azad university, mashhad branch, mashhad, iran

سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)

ملیحه بهادران | malihe bahadoran
a. islamic azad university, mashhad branch, mashhad, iran b. members of mashhad neuroscience research group of islamic azad university, mashhad branch, mashhad, iran

سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)

بیتا زرگران | bita zargaran
a. islamic azad university, mashhad branch, mashhad, iran b. members of mashhad neuroscience research group of islamic azad university, mashhad branch, mashhad, iran

سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)

نشانی اینترنتی http://shefayekhatam.ir/browse.php?a_code=A-10-24-908&slc_lang=en&sid=fa
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/337/article-337-393362.pdf
کد مقاله (doi)
زبان مقاله منتشر شده fa
موضوعات مقاله منتشر شده تحقیقات پایه در علوم اعصاب
نوع مقاله منتشر شده مروری
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