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Iranian Journal of Veterinary Science and Technology، جلد ۵، شماره ۲، صفحات ۹-۰
عنوان فارسی
چکیده فارسی مقاله
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عنوان انگلیسی Effects of dietary melatonin supplementation on some blood oxidative status biomarkers and biochemical parameters in common carp (Cyprinus carpio)
چکیده انگلیسی مقاله This study was conducted to evaluate the effect of dietary melatonin supplementation (10 mg/kg body wt. for 4 weeks) on some erythrocytic antioxidant enzymes and lipid peroxidation as well as some plasma biochemical parameters in common carp. The results showed that the activities of glutathione peroxidase and superoxide dismutase were increased significantly (p < 0.05) after melatonin supplementation, whereas alterations in catalase activity were not significant. Malondildehyde concentrations in erythrocyte hemolysate were decreased significantly as a result of melatonin treatment. Plasma biochemical analysis revealed a significant decrease of glucose, cholesterol, albumin and triglyceride, in addition to a significant increase in total protein, AST and ALP values when compared to the control group. However, alterations in creatinine, urea and LDH levels were not significant following melatonin supplementation compared to the control values. These results offer that pharmacological amounts of melatonin effectively improve erythrocytic oxidative status biomarkers and also alter some plasma biochemical parameters in the common carp that some of them may be undesirable. However, more investigations are required to elucidate the pharmacokinetic effects of melatonin and also possible undesirable effects of high doses of this compound.
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نویسندگان مقاله حمیده قدرتی آزادی | hamideh ghodrati azadi


حسن باغیشنی | hasan baghishani


داور شاهسونی | davar shahsavani


نشانی اینترنتی http://ijvst.um.ac.ir/index.php/veterinary/article/view/17601
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/468/article-468-393534.pdf
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده Original Articles
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