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Acta Medica Iranica، جلد ۵۵، شماره ۴، صفحات ۲۵۴-۲۵۸
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی The Comparative Study of Ondansetron and Metoclopramide Effects in Reducing Nausea and Vomiting After Laparoscopic Cholecystectomy
چکیده انگلیسی مقاله Postoperative nausea and vomiting (PONV) are one of the most common complications of anesthesia and without prophylactic intervention occurs by about one-third of patients under general anesthesia. The aim of this study was to compare the efficacy of ondansetron and metoclopramide in reducing PONV after laparoscopic cholecystectomy. In this study, 60 patients undergoing laparoscopic cholecystectomy were randomly allocated into two equal groups (n=30), and in the first group 10 mg metoclopramide and in the second group 4 mg ondansetron preoperatively were injected. Nausea and vomiting and the need for rescue antiemetic treatment in recovery and 6 hr. and 6-24 hrs. After surgery were evaluated. Data were analyzed by SPSS software with chi-square test and analysis of variance (ANOVA). The incidence of nausea in metoclopramide was 43.3 % and in ondansetron was 33.3 %. The difference between two groups was not significant ( P =0.6). The incidence of vomiting in metoclopramide was 20% and in ondansetron was 26.7%, and there was not any significant difference between intervention groups ( P =0.12). For prevention of PONV after laparoscopic cholecystectomy, both metoclopramide and ondansetron are effective, and in preventing of nausea, ondansetron is more effective than metoclopramide, whereas there was not any significant difference between two drugs in preventing of vomiting.
کلیدواژه‌های انگلیسی مقاله Ondansetron,Metoclopramide,Laparoscopic cholecystectomy,PONV
نویسندگان مقاله خاطره عیسی زاده فر | khatereh isazadehfar
department of community and preventive medicine, ardabil university of medical sciences, ardabil, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اردبیل (Ardabil university of medical sciences)

مسعود انتظاری اصل | masoud entezariasl
department of anesthesiology, ardabil university of medical sciences, ardabil, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اردبیل (Ardabil university of medical sciences)

بیتا شهباززادگان | bita shahbazzadegan
department of nursing, school of medicine, ardabil university of medical sciences, ardabil, iran. and department of public health, school of health, shahid beheshti university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (Shahid beheshti university of medical sciences)

زهرا نورانی | zahra nourani
general practitioner, school of medicine, ardabil university of medical sciences, ardabil, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اردبیل (Ardabil university of medical sciences)

یوسف شفایی | yousef shafaee
department of surgery, school of medicine, iran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)

نشانی اینترنتی http://acta.tums.ac.ir/index.php/acta/article/view/5813
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/56/article-56-398172.pdf
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Articles
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