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Iranian Journal of Pathology، جلد ۱۲، شماره ۲، صفحات ۱۸۳-۱۸۸
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Sero-prevalence of Helicobacter pylori Infection in Neyshabur, Iran, During 2010-2015
چکیده انگلیسی مقاله Backgrounds & Objective: The Helicobacter pylori prevalence has continuously decreased during recent years in Iran. The current study aimed at determining H. pylori prevalence in Neyshabur city, Northeast Iran, during 2010-2015. Methods: The current epidemiologic survey was conducted in Neyshabur from 2010 to 2015 to determine the prevalence of H. pylori infection. A total of 11596 participants (3681 male with the mean age of 31.7±6.2 years and 7915 female with mean age of 68.3±4.7 years) were included. The enzyme-linked immunosorbent assay kits for the detection of H. pylori and Stat Fax 3200® Microplate Reader (USA) with a sensitivity of 95% and specificity of 98% were used. Titers above 12 units were considered positive for IgG, IgA, and IgM (negative < 8, equivocal 8 to 12, and positive >12 U). The Chi-square t test and F test were used to analyze data. Results: The overall IgA, IgG, and IgM seropositive samples among the study participants were 852 (7.2%), 9000 (72.8%), and 1256 (5.2%), respectively. The IgA seropositivity was significantly high among the age group above 51 years, compared with the other age groups. Moreover, the IgG and IgM seropositivity were significantly high among the age groups 41 to 50 and 31 to 40 years respectively, compared with the other age groups. There was no significant difference between male and female cases regarding IgA and IgG seropositive samples, but IgM level was significantly higher among females, compared with that of the male cases. Furthermore, there was no significant alteration in IgA, IgG, and IgM seropositivity during 2010-2014 in Neyshabur. Conclusion: The prevalence of H. pylori in Neyshabur was high in the healthy population. Furthermore, the H. pylori prevalence did not change from 2010 to 2014 in the studied city. Effective approaches to improve health, educational, and socioeconomic status should be implemented to minimize and control H. pylori infection.
کلیدواژه‌های انگلیسی مقاله Helicobacter pylori, Sero-Prevalence, Neyshabur City, ELISA
نویسندگان مقاله محمد صالحی |
medical diagnostic laboratory of neyshabour, center of medical, pathological and genetic diagnostic services, iranian academic center for education, culture and research acecr , mashhad branch, mashhad, iran

عبدالمجید قاسمیان |
microbiology department, faculty of medicine, aja university of medical sciences, tehran, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)

سید خلیل شکوهی مصطفوی | seyyed khalil shokouhi mostafavi
dept. of microbiology, tehran medical sciences branch, islamic azad university, tehran, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی ارتش (Artesh university of medical sciences)

سمیه نجفی |
dept. of microbiology, faculty of biological sciences, islamic azad university, tonekabon branch, tonekabon, iran
سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)

حسن رجبی وردنجانی | rajabi vardanjani
researcher of shahrekord university of medical sciences, shahrekord, iran
سازمان اصلی تایید شده: دانشگاه آزاد اسلامی تنکابن (Islamic azad university of tonekabon)

نشانی اینترنتی http://ijp.iranpath.org/article_25037_f27e10c92d461d7ff200719aac246461.pdf
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/194/article-194-401479.pdf
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده 8
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