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Journal of Medical Microbiology and Infectious Diseases، جلد ۳، شماره ۳، صفحات ۷۱-۷۴
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Phytochemical Composition and Antibacterial Activity of Trachyspermum copticum L. essential oil, East Azerbaijan, Iran
چکیده انگلیسی مقاله Introduction: The aim of this study was to characterize the chemical composition and antimicrobial activity of Trachyspermum copticum essential oil (EO). Methods: The chemical composition of seed samples obtained from Mianeh city in East Azerbaijan, was assessed using gas chromatography-mass spectrometry (GC-MS). The antimicrobial activity was evaluated by disc diffusion method against methicillin-resistant Staphylococcus aureus (MRSA), other extended-spectrum beta-lactamases (ESBLs) producing, as well as Gram-negative and Gram-positive bacteria. The minimum inhibitory concentration (MIC) value of EO was assessed using agar dilution method. Results: Thirteen monoterpene hydrocarbons (57.6%) and oxygenated monoterpenes (42.4%) compounds were identified in the EO, of which, 3 compounds, including thymol, m-cymene, and, γ-terpinene were the major components of the EO with quantities of 41.9, 33.53, and 20.42%, respectively. The EO showed antimicrobial activity against ten microorganisms, especially Streptococcus sanguis, S. aureus (MRSA strain), and Klebsiella pneumoniae (ESBL-producing strain), which was potentially better than tetracycline and kanamycin. Conclusion: This study confirmed that EO of T. copticum has in vitro antimicrobial activity against Gram-negative and Gram-positive bacteria, which has made it an alternative antibacterial agent.
کلیدواژه‌های انگلیسی مقاله Phytochemicals, Trachyspermum copticum, Essential Oil
نویسندگان مقاله هایده مبین | haedeh mobaiyen
tabriz, manzareh ave, medicine faculty, islamic azad university

سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)

میثم nasarollah پور | maisam nasarollah pour
tabriz, manzareh ave, medicine faculty, islamic azad university

سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)

فرانک علمی | franak elmi
tabriz, manzareh ave, medicine faculty, islamic azad university

سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)

نشانی اینترنتی http://jommid.pasteur.ac.ir/browse.php?a_code=A-10-54-2&slc_lang=en&sid=en
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/350/article-350-409101.pdf
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Other
نوع مقاله منتشر شده Original article
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