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Acta Medica Iranica، جلد ۵۵، شماره ۵، صفحات ۳۳۳-۳۳۹
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عنوان انگلیسی The Correlation Between Liver Fat Content and Ulcerative Colitis Disease Severity
چکیده انگلیسی مقاله To evaluate the association between disease severity and hepatic steatosis in patients with ulcerative colitis (UC) and non-alcoholic steatohepatitis (NASH). Consecutively selected UC patients admitted to the gastroenterology clinic were enrolled in the study. UC severity was assessed by Truelove and Witts classification. Patients with severe UC were excluded from the study. NASH was determined based on persistently elevated serum aminotransferase levels and detection of fatty liver ultrasound. Patients with other etiologies for elevated aminotransferase levels were excluded. Liver fat content (LFC) was assessed by measuring liver fat score (LFS). One hundred patients (42% male) were included in the study. According to liver ultrasound examination, 62 (%) patients were identified with grade 1 fatty liver disease, and 38 (%) patients were classified as advanced (grade 2 and 3) fatty liver disease. Sixty-one patients had left-sided UC and (46%) had mild UC disease severity index. LFS was significantly higher in UC patients with the moderate disease than patients with mild disease (3.53±2.68 vs. 5.89±2.85, respectively; P < 0.01). Nevertheless, no significant difference was observed in LFS regarding UC extension. There was no significant difference between NASH ultrasound grades in view of UC severity and extension. LFC might be associated with UC severity.
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله رایکا جمالی | raika jamali
research development center of sina hospital, digestive disease research institute, ibd research center, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

محمد بیگلری | mohammad biglari
department of internal medicine, sina hospital, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

سید وحید سید حسینی | seyyed vahid seyyed hosseini
department of internal medicine, sina hospital, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

علی شکوری راد | ali shakouri rad
department of radiology, sina hospital, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

فرید کوثری | farid kosari
department of pathology, sina hospital, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

نشانی اینترنتی http://acta.tums.ac.ir/index.php/acta/article/view/6094
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/56/article-56-415953.pdf
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Articles
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