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Journal of Research in Medical Sciences، جلد ۲۲، شماره ۲، صفحات ۰-۰

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عنوان انگلیسی Omega-3 supplementation effects on polycystic ovary syndrome symptoms and metabolic syndrome
چکیده انگلیسی مقاله Background: Polycystic ovary syndrome (PCOS) is the most common female endocrine disorder with unknown etiology andwith different complications. The aim of this study was to evaluate the effect of omega?3 supplementation on PCOS symptomsand metabolic syndrome. Materials and Methods: This double?blind clinical trial was performed in 2015 in Alzahra and ShahidBeheshti Hospitals, Isfahan, Iran, on 88 patients with PCOS. Intervention group took omega?3 supplements with dose of 2 g/dayfor 6 months (two capsules), but control group received two olive oil capsules. Finally, ultrasound and laboratory findings and therecovery rate of menstrual disorders in both groups were compared. Results: After 6 months’ intervention, waist circumference (WC)was significantly lower in omega?3 as compared to control (81.18 ± 2.87 vs. 84.22 ± 2.61 cm, respectively, P < 0.0001). High?densitylipoprotein was increased (47.2 ± 1.37 vs. 41.56 ± 1.34 mg/dl, respectively, P < 0.0001) while low?density lipoprotein (107.79 ± 1.68 vs.117.4 ± 1.57 mg/dl, respectively), triglyceride (116.02 ± 3.13 vs. 125.06 ± 2.91 mg/dl, respectively), and cholesterol (180.34 ± 6.34 vs.189.56 ± 5.93 mg/dl, respectively) in omega?3 were significantly lower than control (P < 0.0001). The interval between periods inomega?3 was significantly shorter than control (29.83 ± 4.68 vs. 47.11 ± 8.72 days, respectively, P < 0.001). Conclusion: Omega?3improves lipid profiles decrease, WC, and interval between periods while weight, hip circumference, fasting blood sugar, number ofovarian follicle, size of ovary, bleeding volume, menstrual bleeding, and hirsutism score did not change by administration of omega?3. Key words: Metabolic syndrome, omega?3, polycystic ovary syndrome
کلیدواژه‌های انگلیسی مقاله Metabolic syndrome, omega-3, polycystic ovary syndrome

نویسندگان مقاله بهناز خانی | behnaz khani
department of obstetrics and gynecology, school of medicine, isfahan university of medical sciences

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

farhanaz مردانی | farhanaz mardani
department of obstetrics and gynecology, school of medicine, isfahan university of medical sciences

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

sajadeh جعفری فشارکی | sajadeh jafari fesharaki
department of obstetrics and gynecology, student research committee, school of medicine, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)


نشانی اینترنتی http://jrms.mui.ac.ir/index.php/jrms/article/view/10645
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/218/article-218-421758.pdf
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده Original Articles
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