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Veterinary Research Forum، جلد ۸، شماره ۳، صفحات ۱۷۹-۱۸۴

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عنوان انگلیسی Evaluation of Pasteurella multocida serotype B:2 resistance to immune serum and complement system
چکیده انگلیسی مقاله Members of gram-negative bacteria family Pasteurellaceae, include a large number of important economically human and veterinary pathogens. Organisms belonging to the family can colonize in mucosal surfaces of the respiratory, alimentary, genital tracts and cause diseases in various mammals, birds, and reptiles. Hemorrhagic septicemia is an acute disease of cattle and buffaloes in tropical countries caused by Pasteurella multocida serotype B:2. In the present study, the possible bactericidal activity of immune calf sera in the presence and absence of complement system was investigated. The results showed that P. multocida B:2 is highly resistant to positive serum, containing high levels of IgG and IgM obtained from calves after vaccination, and complement activity in normal fresh calf serum. This organism also grew rapidly in the normal fresh calf serum and the mixture of positive serum as well as normal fresh calf serum. As a control test an E. coli strain was subjected to the same experiment and found completely sensitive to the bactericidal activity of complement in calf and guinea pig fresh sera. Results were indicative of the presence of inhibitory mechanism(s) in P. multocida B:2 against bactericidal activity of immune calf serum and complement system.
کلیدواژه‌های انگلیسی مقاله Cattle, Complement, Hemorrhagic septicemia, Pasteurella

نویسندگان مقاله سعید عطایی کچویی | ataei kachooei
department of bacterial poultry diseases, razi vaccine and serum research institute, agricultural research, education and extension organization areeo , karaj, iran
سازمان اصلی تایید شده: موسسه تحقیقات واکسن و سرم سازی رازی (Razi vaccine and serum research institute)

محمد مهدی رنجبر | mohammad mehdi
department of animal virology, razi vaccine and serum research institute, agricultural research, education and extension organization areeo , karaj, iran
سازمان اصلی تایید شده: موسسه تحقیقات واکسن و سرم سازی رازی (Razi vaccine and serum research institute)

صبا عطایی کچویی | ataei kachooei
department of life sciences, faculty of life sciences, kharazmi university, karaj, iran


نشانی اینترنتی http://vrf.iranjournals.ir/article_27365_4314a25d6393d8670e4a54351c9e3a3b.pdf
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/544/article-544-429404.pdf
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زبان مقاله منتشر شده en
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