این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Research Journal of Pharmacognosy، جلد ۴، شماره ۴، صفحات ۱۷-۲۲
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Coumaroyl flavone glycosides and cinammic acid derivatives from the aerial parts of Phlomis bruguieri Desf.
چکیده انگلیسی مقاله Background and objectives: Phlomis bruguieri Desf. (Lamiaceae) is a perennial herbaceous plant distributed in Iran, Turkey and Iraq. Despite medicinal potentials of this species, the current knowledge on its phytochemical constituents is limited. The aim of the present study was to investigate the phytochemical constituents of the essential oil and various extracts of this species. Methods: Essential oils of the plant aerial parts were extracted by hydrodistillation and steam distillation methods and analysed using GC and GC/MS.Column chromatography with silica gel (normal and reversed phases) and Sephadex LH-20 were also used for the isolation of compounds from various extracts obtained from P. bruguieri aerial parts. The structures of isolated compounds were established by 1D and 2D NMR techniques. Results: By GC and GC/MS analysis, germacrene D (29.8%), apiole (20.7%) and myristicin (16.63%) were identified as the main compounds of hydrodistilled oil. Apiole (53.20%) and myristicin (34.87%) were also detected as the main compounds of the oil extracted by steam distillation method. Phytochemical analysis of the plant extracts resulted in the isolation and structural elucidation of  β-sitosterol (1), p-coumaric acid methyl ester (2), chrysoeriol 7-O-(3''-(E)-p-coumaroyl)-β-D-glucopyranoside (3), chrysoeriol 7-O-(3'',6''-di-O-(E)-p-coumaroyl)-β-D glucopyranoside (4), chrysoeriol 7-O-β-D-glucopyranoside (5), chlorogenic acid (6) and verbascoside (7). Conclusion: the results of the present study introduce steam distilled oil of P. bruguieri as a new source of apiole and myristicin. Moreover, identification of coumaroyl flavone glycosides and cinammic acid derivatives from the aerial parts of this species highlighted the species as a good candidate for further biological and pharmacological studies.
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله محمدرضا delnavazi | m r
department of pharmacognosy, faculty of pharmacy, tehran university of medical sciences, tehran, iran.
سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

m صفایی |
department of pharmacognosy, faculty of pharmacy, tehran university of medical sciences, tehran, iran.
سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

s بیوکی |
department of pharmacognosy, faculty of pharmacy, tehran university of medical sciences, tehran, iran.
سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

s توکلی |
department of pharmacognosy, faculty of pharmacy, tehran university of medical sciences, tehran, iran.
سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

m aghaahmadi |
department of biology, faculty of science, university of isfahan, isfahan, iran.
سازمان اصلی تایید شده: دانشگاه اصفهان (Isfahan university)

a حاجی آخوندی |
department of pharmacognosy, faculty of pharmacy, tehran university of medical sciences, tehran, iran.
سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

n یاسا |
department of pharmacognosy, faculty of pharmacy, tehran university of medical sciences, tehran, iran.
سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

نشانی اینترنتی http://www.rjpharmacognosy.ir/article_50341_fef5ff23da9e3b37a6fbacc976c108b8.pdf
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/338/article-338-432412.pdf
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات