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Iranian Journal of Public Health، جلد ۴۳، شماره ۶، صفحات ۶۹۶-۷۰۴
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عنوان انگلیسی Metallothionein Lower Under-Expression in Benign Tumors than That in Malignant Tumors: Systematic Review Article and Meta-Analysis.
چکیده انگلیسی مقاله Metallothionein (MT) manifests varying expression levels in carcinomas, and they may be considered as valuable cell cancerization biomarkers for diagnosis of patients with cancers. A meta-analysis was conducted to evaluate comprehensively the MT expression difference in various benign tumors and malignant tumors, which compared the high with low MT expression levels in patients of the available studies. Finally, a total of 13 studies dealing with various tumors were involved for this meta-analysis. The results indicated that lower expression of MT in various benign tumors tissue than that in corresponding malignant tumors with the pooled OR of 0.52 (95 % CI 0.18-1.47, P < 0.001). In conclusion, MT expression difference is associated with tumor various stages in tumor patients and could be a useful clinical criteria of distinguishing benign tumors and malignant tumors for those patients.
کلیدواژه‌های انگلیسی مقاله Benign tumors,Malignant tumors,Meta-analysis,Metallothionein
نویسندگان مقاله jie زانگ | jie zhang
1. key laboratory of biomedical engineering amp;amp; technology of shandong high school, shandong wanjie medical college , zibo, china.


ruijie سون | ruijie sun
2. dept. of medicine, shandong wanjie medical college , zibo, china.


yue liu | yue liu
1. key laboratory of biomedical engineering amp;amp; technology of shandong high school, shandong wanjie medical college , zibo, china.


guinian ونگ | guinian wang
3. dept. of laboratory medicine, the first hospital of zibo city , zibo, china.


qinglu ونگ | qinglu wang
1. key laboratory of biomedical engineering amp;amp; technology of shandong high school, shandong wanjie medical college , zibo, china.
نشانی اینترنتی http://ijph.tums.ac.ir/index.php/ijph/article/view/4080
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