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Iranian Journal of Medical Sciences، جلد ۴۲، شماره ۵، صفحات ۴۴۳-۰
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عنوان انگلیسی Multilocus Sequence Typing of the Clinical Isolates of Salmonella Enterica Serovar Typhimurium in Tehran Hospitals
چکیده انگلیسی مقاله Background: Salmonella enterica serovar Typhimurium is one of the most important serovars of Salmonella enterica and is associated with human salmonellosis worldwide. Many epidemiological studies have focused on the characteristics of Salmonella Typhimurium in many countries as well as in Asia. This study was conducted to investigate the genetic characteristics of Salmonella Typhimurium using multilocus sequence typing (MLST). Methods: Clinical samples (urine, blood, and stool) were collected from patients, who were admitted to 2 hospitals in Tehran between April and September, 2015. Salmonella Typhimurium strains were identified by conventional standard biochemical and serological testing. The antibiotic susceptibility patterns of the Salmonella Typhimurium isolates against 16 antibiotics was determined using the disk diffusion assay. The clonal relationship between the strains of Salmonella Typhimurium was analyzed using MLST. Results: Among the 68 Salmonella isolates, 31% (n=21) were Salmonella Typhimurium. Of the total 21 Salmonella Typhimurium isolates, 76% (n=16) were multidrug-resistant and showed resistance to 3 or more antibiotic families. The Salmonella Typhimurium isolates were assigned to 2 sequence types: ST19 and ST328. ST19 was more common (86%). Both sequence types were further assigned to 1 eBURST group. Conclusion: This is the first study of its kind in Iran to determine the sequence types of the clinical isolates of Salmonella Typhimurium in Tehran hospitals using MLST. ST19 was detected as the major sequence type of Salmonella Typhimurium.
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نویسندگان مقاله رضا رنجبر | reza ranjbar
department of microbiology, faculty of sciences, tonekabon branch, islamic azad university, tonekabon, iran

سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)

پریسا الحاقی | parisa elhaghi
department of laboratory medical sciences, faculty of paramedical sciences, ahvaz jundishapur university of medical sciences, ahvaz, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی جندی شاپور اهواز (Ahvaz jundishapur university of medical sciences)

لیلی شکوهی زاده | leili shokoohizadeh


نشانی اینترنتی http://ijms.sums.ac.ir/index.php/IJMS/article/view/2999
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/147/article-147-433330.pdf
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Article(s)
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